Product image of Irbesartan Abz (Irbesartan) supplied by GNH India

Irbesartan Abz

Active Ingredient:
Irbesartan
Origin:
EU

Irbesartan Abz (Irbesartan)

Irbesartan, the active ingredient in Irbesartan Abz, is an angiotensin II receptor blocker presented as an oral dosage form for oral administration. It works by selectively blocking AT1 receptors, which helps to lower elevated blood pressure and reduces progression of kidney damage in patients with diabetic nephropathy.

GNH India supplies Irbesartan Abz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across global markets.

Manufacturer / TM Owner

Abz-Pharma Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Irbesartan acts on the renin‑angiotensin‑aldosterone system to control blood pressure and protect renal function.

  • Hypertension: lowers systolic and diastolic blood pressure in adults with essential hypertension.
  • Diabetic nephropathy: slows the decline of renal function in patients with type 2 diabetes and proteinuria.
  • Renal protection in type 2 diabetes: reduces progression of kidney disease associated with diabetic nephropathy.

How It Works

  • Irbesartan selectively antagonizes angiotensin II type 1 (AT1) receptors on vascular smooth muscle and adrenal tissue. By blocking these receptors, it prevents angiotensin II‑mediated vasoconstriction and aldosterone secretion, leading to vasodilation, reduced peripheral resistance, and decreased sodium‑water retention, which together lower arterial pressure and mitigate renal damage.

Side Effects

Common Side Effects

  • Dizziness: feeling light‑headed, especially after the first dose.
  • Headache: mild to moderate intensity.
  • Fatigue: general tiredness without a clear cause.
  • Upper respiratory tract infection: nasopharyngitis or mild cough.
  • Hyperkalemia (mild): elevated serum potassium levels.

Serious or Rare Side Effects

  • Angioedema: swelling of face, lips, tongue, or throat requiring immediate medical attention.
  • Severe hyperkalemia: markedly high potassium that can affect cardiac rhythm.
  • Acute renal failure: sudden decline in kidney function.
  • Hepatic injury: abnormal liver enzymes or hepatitis.
  • Myocardial infarction (rare): chest pain or cardiac events.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Blood pressure monitoring: check baseline and periodic readings to avoid hypotension.
  • Renal function assessment: evaluate serum creatinine and eGFR, especially in patients with existing kidney disease.
  • Serum potassium: monitor levels to detect hyperkalemia early.
  • Pregnancy: contraindicated in pregnancy (Category D) due to fetal toxicity risk.
  • Elderly patients: start at lower doses and monitor for orthostatic symptoms.
  • Store at room temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Irbesartan may interact with several medicines that affect potassium balance or renal function.

Major Interactions (Avoid)

  • Aliskiren (in diabetic patients): combined use can increase renal impairment and hyperkalemia.
  • Potassium‑sparing diuretics (e.g., spironolactone): risk of severe hyperkalemia.
  • ACE inhibitors (e.g., enalapril): additive effect on potassium and renal function.

Moderate Interactions (Monitor Closely)

  • Thiazide diuretics: may enhance antihypertensive effect, requiring dose adjustment.
  • CYP2C9 inhibitors (e.g., fluconazole): can increase irbesartan plasma concentrations.
  • NSAIDs (e.g., ibuprofen): may reduce antihypertensive efficacy and affect renal function.

Frequently Asked Questions

Irbesartan Abz is prescribed for the management of essential hypertension and to slow the progression of kidney disease in patients with diabetic nephropathy. By lowering blood pressure and reducing proteinuria, it helps protect cardiovascular and renal health in these populations.

Irbesartan blocks angiotensin II type 1 (AT1) receptors, preventing angiotensin II from causing vasoconstriction and stimulating aldosterone release. This results in relaxed blood vessels, lower peripheral resistance, reduced sodium and water retention, and ultimately a decrease in blood pressure and renal stress.

The appropriate dose of Irbesartan Abz is determined by the prescribing clinician based on the individual’s blood pressure, kidney function, and overall health status. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

Irbesartan is classified as Pregnancy Category D, indicating evidence of fetal risk and it should be avoided in pregnancy. Limited data are available for breastfeeding; therefore, the drug is generally not recommended for nursing mothers unless the potential benefit outweighs the risk.

To place an order, submit an enquiry on the Irbesartan Abz product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Irbesartan belongs to the angiotensin II receptor blocker (ARB) class, offering similar blood‑pressure‑lowering efficacy to ACE inhibitors but with a lower incidence of cough and angioedema. Compared with calcium‑channel blockers, ARBs act on the renin‑angiotensin system rather than directly on vascular smooth muscle calcium channels.

Irbesartan Abz should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiry date printed on the label.

Irbesartan Abz is taken orally, usually once daily with or without food. The tablet should be swallowed whole with a glass of water. Patients should follow the dosing schedule prescribed by their healthcare professional.

The most serious risks include angioedema, severe hyperkalemia, and acute renal failure. Patients should seek immediate medical attention if they experience swelling of the face or throat, marked muscle weakness, irregular heartbeat, or a sudden decline in kidney function.

Irbesartan Abz is contraindicated in patients with known hypersensitivity to irbesartan or any ARB, in pregnant women, and in individuals with severe hepatic impairment. Caution is also advised for patients with bilateral renal artery stenosis or those taking interacting medications that could raise potassium levels.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Irbesartan

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT