Product image of Irbesartan Aurobindo (Irbesartan) supplied by GNH India

Irbesartan Aurobindo

Active Ingredient:
Irbesartan
Origin:
EU

Irbesartan Aurobindo (Irbesartan)

Irbesartan, the active ingredient in Irbesartan Aurobindo, is an Angiotensin II receptor blocker (ARB) presented as an oral tablet for oral use. It is employed to manage high blood pressure and to protect kidney function in patients with diabetic kidney disease.

GNH India supplies Irbesartan Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for each batch. Customers benefit from reliable delivery timelines and comprehensive post‑sale support.

Manufacturer / TM Owner

Puren Pharma Gmbh & Co. Kg

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Irbesartan acts on the renin‑angiotensin‑aldosterone system to lower blood pressure and protect renal function.
  • Hypertension: reduces systolic and diastolic blood pressure in adult patients.
  • Diabetic nephropathy: slows progression of kidney damage and reduces proteinuria in type 2 diabetes.
  • Proteinuria: decreases urinary protein excretion in patients with renal disease.

How It Works

  • Irbesartan selectively blocks angiotensin II type 1 (AT1) receptors on vascular smooth‑muscle cells, adrenal glands, kidneys and the heart. By preventing angiotensin II binding, it inhibits vasoconstriction, aldosterone secretion and sympathetic activation, leading to vasodilation, reduced sodium‑water retention and lowered blood pressure, while also mitigating renal and cardiac remodeling. The blockade also improves endothelial function and reduces inflammatory mediators associated with hypertension.

Side Effects

Irbesartan may be associated with a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Dizziness
  • Headache
  • Fatigue

Serious or Rare Side Effects

  • Angioedema
  • Hyperkalemia
  • Acute kidney injury

Precautions & Warnings

When prescribing Irbesartan, clinicians should consider several safety measures.

  • Monitor blood pressure regularly: ensure therapeutic targets are met and avoid excessive hypotension.
  • Assess renal function before and during therapy: check serum creatinine and eGFR.
  • Check serum potassium levels periodically: detect hyperkalemia early.
  • Use caution in patients with hepatic impairment: dose adjustment may be required.
  • Avoid use in pregnancy unless benefits outweigh risks: teratogenic potential is unknown.
  • Store at room temperature: keep in the original container, protect from moisture.

Avoid Interactions

Irbesartan can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Aliskiren (in diabetes): combined use may increase risk of renal impairment.
  • ACE inhibitors: concurrent use can cause severe hyperkalemia.
  • Potassium‑sparing diuretics: may lead to dangerous elevations in serum potassium.

Moderate Interactions (Monitor Closely)

  • NSAIDs: can blunt antihypertensive effect and affect renal function.
  • Thiazide diuretics: may enhance hypotensive response.
  • CYP3A4 inhibitors (e.g., ketoconazole): may increase Irbesartan plasma concentrations.

Frequently Asked Questions

Irbesartan Aurobindo is an oral Angiotensin II receptor blocker indicated for the treatment of hypertension and for slowing the progression of diabetic nephropathy, helping to control blood pressure and protect kidney function in adults.

Irbesartan selectively blocks AT1 receptors, preventing angiotensin II from causing vasoconstriction and aldosterone release. This results in vasodilation, reduced sodium and water retention, lower blood pressure, and decreased stress on the heart and kidneys.

The appropriate dose of Irbesartan is determined by the prescribing healthcare professional based on the patient’s condition, blood pressure response, renal function and other individual factors. Dosage adjustments are made according to clinical judgment.

Safety of Irbesartan during pregnancy has not been established, and it is generally avoided because of potential fetal risk. Limited data are available for breastfeeding; therefore, use is usually discouraged unless the benefit clearly outweighs the potential risk.

To place an order, submit an enquiry on the Irbesartan Aurobindo product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with ACE inhibitors, Irbesartan offers a similar blood‑pressure‑lowering effect but with a lower incidence of cough. Unlike calcium‑channel blockers, it directly targets the renin‑angiotensin system, providing additional renal‑protective benefits, especially in patients with diabetic kidney disease.

Irbesartan tablets should be stored at room temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments.

Irbesartan is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water. Patients should follow the prescribing clinician’s instructions regarding timing and any required dose adjustments.

The most serious adverse reactions include angioedema (rapid swelling of the face, lips, tongue or throat), hyperkalemia (elevated blood potassium), and acute kidney injury. Patients should seek immediate medical attention if they experience swelling, severe dizziness, or sudden changes in kidney function.

Irbesartan should be avoided in individuals with known hypersensitivity to the drug, severe hepatic impairment, or in pregnant women unless the potential benefit justifies the risk. Patients with uncontrolled hyperkalemia or severe renal artery stenosis should also not use this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.