Product image of Irbesartan Eg (Irbesartan) supplied by GNH India

Irbesartan Eg

Active Ingredient:
Irbesartan
Origin:
EU

Irbesartan Eg (Irbesartan)

Irbesartan, the active ingredient in Irbesartan Eg, is an Angiotensin II receptor blocker (ARB) presented as an oral tablet for systemic use. It is indicated for the management of hypertension and for slowing the progression of diabetic nephropathy in adult patients, and is marketed in the European Union.

GNH India supplies Irbesartan Eg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing consistent product quality, regulatory adherence, and reliable logistics to meet the needs of healthcare providers across multiple regions.

Manufacturer / TM Owner

Eurogenerics N.V./S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Irbesartan acts on the renin‑angiotensin system to control blood pressure and protect kidney function.
  • Hypertension: lowers systolic and diastolic blood pressure, reducing cardiovascular risk.
  • Diabetic nephropathy: slows progression of renal impairment in patients with type 2 diabetes.
  • Proteinuria: decreases urinary protein excretion, supporting kidney health.

How It Works

  • Irbesartan selectively blocks angiotensin II type 1 (AT1) receptors on vascular smooth‑muscle cells, adrenal glands, and renal tissue. By preventing angiotensin II from binding, it inhibits vasoconstriction, aldosterone release, and sympathetic activation, leading to vasodilation, reduced sodium and water retention, and lower systemic blood pressure. The blockade also diminishes intraglomerular pressure, contributing to renal protection in diabetic patients.

Side Effects

Irbesartan may be associated with a range of adverse reactions, which are categorized by frequency.

Common Side Effects

  • Dizziness: sensation of light‑headedness, especially after standing.
  • Headache: mild to moderate intensity.
  • Fatigue: general feeling of tiredness.
  • Upper respiratory tract infection: nasopharyngitis or mild cough.

Serious or Rare Side Effects

  • Hyperkalemia: elevated blood potassium levels, potentially dangerous.
  • Acute kidney injury: sudden decline in renal function.
  • Angioedema: swelling of face, lips, tongue, or airway.
  • Hepatic dysfunction: abnormal liver enzymes or hepatitis.

Precautions & Warnings

  • When prescribing Irbesartan, clinicians should consider several safety aspects.
  • Monitor blood pressure: ensure adequate control without excessive hypotension.
  • Assess renal function: check serum creatinine and eGFR before and during therapy.
  • Check serum potassium: avoid hyperkalemia, especially with potassium‑sparing diuretics.
  • Contraindicated in: patients with known hypersensitivity to Irbesartan or other ARBs.
  • Store at ambient temperature: keep below 25 °C, protect from moisture and light in original container.

Avoid Interactions

Irbesartan can interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid)

  • Aliskiren (in diabetic patients): increased risk of renal impairment and hyperkalemia.
  • Potassium‑supplementing agents or potassium‑sparing diuretics: may cause dangerous hyperkalemia.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may reduce antihypertensive effect and affect renal function.
  • ACE inhibitors or other ARBs: additive risk of hypotension, hyperkalemia, renal dysfunction.
  • Diuretics (especially thiazides): may enhance antihypertensive response; monitor electrolytes.

Frequently Asked Questions

Irbesartan Eg is used to treat high blood pressure (hypertension) and to slow the progression of kidney damage in patients with diabetic nephropathy. By lowering systemic vascular resistance, it helps reduce the risk of cardiovascular events and supports renal function in eligible adults.

Irbesartan works by selectively blocking angiotensin II type 1 (AT1) receptors. This prevents angiotensin II from causing vasoconstriction and aldosterone release, leading to vessel relaxation, reduced sodium and water retention, lower blood pressure, and decreased pressure within the kidney’s filtering units.

The appropriate dose of Irbesartan is determined by the prescribing healthcare professional based on the individual’s medical condition, response to therapy, and any concomitant medications. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Irbesartan is generally not recommended for use during pregnancy because it may affect fetal kidney development. Safety during breastfeeding has not been established, so a healthcare provider should be consulted before use in nursing mothers.

To order Irbesartan Eg, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Irbesartan belongs to the ARB class, which blocks the effects of angiotensin II without affecting bradykinin levels, unlike ACE inhibitors. Compared with calcium‑channel blockers or diuretics, ARBs are often better tolerated with fewer cough or electrolyte disturbances, making them a common choice for patients who cannot use ACE inhibitors.

Irbesartan tablets should be stored at ambient temperature, preferably below 25 °C, in their original packaging to protect them from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged.

Irbesartan is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water. Patients should follow the dosing schedule prescribed by their healthcare professional.

Serious risks include hyperkalemia (high potassium levels), acute kidney injury, and angioedema (swelling of the face, lips, tongue, or airway). Patients should seek immediate medical attention if they experience swelling, severe dizziness, or signs of kidney dysfunction such as reduced urine output.

Irbesartan should not be used by individuals with known hypersensitivity to Irbesartan or any other ARB, and it is contraindicated in patients with severe hepatic impairment. Caution is also advised for those with bilateral renal artery stenosis or pregnant women.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.