Product image of Irbesartan Hennig (Irbesartan) supplied by GNH India

Irbesartan Hennig

Active Ingredient:
Irbesartan
Origin:
EU

Irbesartan Hennig (Irbesartan)

Irbesartan, the active ingredient in Irbesartan Hennig, is a Angiotensin II receptor blocker (ARB) presented as a tablet for oral use. It treats hypertension and diabetic nephropathy in adults.

GNH India supplies Irbesartan Hennig as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Hennig Arzneimittel Gmbh & Co. Kg

1
Pack/s
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Indications & Clinical Uses

Irbesartan belongs to the class of Angiotensin II receptor blockers and is used to manage conditions related to the renin‑angiotensin system.

  • Hypertension: lowers elevated blood pressure and reduces cardiovascular risk.
  • Diabetic nephropathy: slows the progression of kidney damage in patients with type 2 diabetes.
  • Proteinuria associated with diabetes: reduces urinary protein excretion, supporting renal protection.

How It Works

  • Irbesartan selectively blocks angiotensin II type 1 (AT1) receptors on vascular smooth muscle and adrenal cells. By preventing angiotensin II binding, it inhibits vasoconstriction and aldosterone release, leading to vasodilation, reduced sodium and water retention, and ultimately lower blood pressure and renal protective effects.

Side Effects

Common Side Effects

  • Dizziness: feeling light‑headed or unsteady.
  • Headache: mild to moderate head pain.
  • Fatigue: unusual tiredness or lack of energy.
  • Upper respiratory tract infection: cold‑like symptoms.
  • Diarrhea: loose stools.
  • Nasal congestion: blocked nose.

Serious or Rare Side Effects

  • Angioedema: swelling of face, lips, tongue, or throat.
  • Hyperkalemia: elevated blood potassium levels.
  • Acute kidney injury: sudden decline in renal function.
  • Hepatic injury: abnormal liver enzymes or hepatitis.
  • Severe hypotension: markedly low blood pressure.
  • Myocardial infarction: rare heart attack events.

Precautions & Warnings

Before initiating Irbesartan, consider the following safety measures.

  • Renal function: monitor serum creatinine and eGFR regularly.
  • Electrolytes: check potassium levels, especially if using potassium‑sparing agents.
  • Pregnancy: avoid use during the first trimester and discuss risks with a healthcare professional.
  • Concomitant potassium‑sparing diuretics: increased risk of hyperkalemia; use with caution.
  • Drug interactions: review all concurrent medications for potential interactions.
  • Store at ambient temperature: keep below 25°C in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Irbesartan may interact with several medicines; awareness helps maintain safety.

Major Interactions (Avoid)

  • ACE inhibitors: combined use raises the risk of angioedema.
  • Potassium supplements or potassium‑sparing diuretics: can cause dangerous hyperkalemia.
  • Aliskiren in diabetic patients: may increase renal adverse effects.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may blunt antihypertensive efficacy and affect renal function.
  • Lithium: Irbesartan can raise lithium concentrations, requiring level checks.
  • Thiazide diuretics: may enhance hypotensive effect; monitor blood pressure.

Frequently Asked Questions

Irbesartan Hennig is prescribed to lower high blood pressure (hypertension) and to slow the progression of kidney damage in patients with diabetic nephropathy. It may also be used to reduce proteinuria associated with diabetes.

Irbesartan blocks the angiotensin II type 1 (AT1) receptors, preventing angiotensin II from causing blood vessels to narrow and the adrenal glands from releasing aldosterone. This leads to vasodilation, reduced fluid retention, and lower blood pressure, while also protecting kidney function.

The appropriate dose of Irbesartan Hennig is determined by the prescribing healthcare professional based on the individual’s medical condition, response to therapy, and other factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Irbesartan is generally not recommended during pregnancy because it may affect fetal development. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss alternative treatments with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Irbesartan belongs to the ARB class, which is often preferred over ACE inhibitors when patients experience cough or angioedema. Compared with calcium‑channel blockers, ARBs provide similar blood‑pressure control but have a distinct renal‑protective benefit in diabetic patients.

Irbesartan Hennig should be stored at ambient temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight, and excessive heat to maintain product stability.

Irbesartan Hennig is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed by a healthcare professional.

Serious risks include angioedema (swelling of the face, lips, tongue, or throat), severe hyperkalemia (high potassium levels), acute kidney injury, and rare cases of hepatic injury. Patients should seek immediate medical attention if they experience any of these symptoms.

Irbesartan Hennig should be avoided in patients with known hypersensitivity to Irbesartan or any ARB component, those with severe renal impairment, and individuals taking concurrent ACE inhibitors or aliskiren (in diabetic patients). Pregnant women should also avoid its use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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