Irbesartan/Hydrocholorthiazide Teva (Hydrochlorothiazide, Irbesartan)

Irbesartan blocks the angiotensin II type 1 (AT1) receptor, preventing vasoconstriction and aldosterone‑mediated sodium retention. Hydrochlorothiazide inhibits sodium‑chloride reabsorption in the distal convoluted tubule, increasing urinary excretion of water and electrolytes. Together they produce additive blood pressure reduction through vasodilation and decreased plasma volume.

The exact dose is determined by the prescribing clinician based on the patient’s blood pressure, renal function, and response to therapy. Physicians typically start with a low‑to‑moderate dose and may adjust it during follow‑up visits to achieve optimal blood pressure control while monitoring safety.

Use during pregnancy is generally discouraged because angiotensin‑II receptor blockers can affect fetal development. Breastfeeding mothers should consult a healthcare professional, as the drug may be excreted in milk. The benefits must outweigh potential risks, and alternative therapies are often preferred.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with other ARB‑thiazide combinations such as Losartan/HCTZ, Irbesartan offers similar blood‑pressure‑lowering efficacy but may have a slightly different side‑effect profile, particularly regarding potassium balance. Choice often depends on individual patient tolerance, renal function, and physician preference.

Store the tablets at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and avoid exposing it to extreme heat or humidity.

The medication is taken orally, usually once daily, with or without food as directed by the prescriber. Swallow the tablet whole with a full glass of water and follow any specific timing instructions provided by the healthcare professional.

Serious adverse events include severe dehydration, acute kidney injury, marked hypotension, and allergic reactions such as angioedema. Patients should be monitored for signs of electrolyte imbalance, especially low potassium, and should seek immediate medical attention if they experience fainting, swelling, or rash.

The drug is contraindicated in patients with severe renal impairment, hyperkalemia, known hypersensitivity to either component, and in pregnant women. Caution is also advised for individuals with severe liver disease or those taking other medications that significantly raise potassium levels.