Product image of Irbesartan Stada (Irbesartan) supplied by GNH India

Irbesartan Stada

Active Ingredient:
Irbesartan
Origin:
EU

Irbesartan Stada (Irbesartan)

Irbesartan, the active ingredient in Irbesartan Stada, is an Angiotensin II receptor blocker presented as an oral tablet for oral use. It is employed to manage high blood pressure and to protect kidney function in patients with diabetic nephropathy. The medication works by selectively blocking AT1 receptors, reducing vasoconstriction and aldosterone-mediated fluid retention.

GNH India supplies Irbesartan Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stadapharm Gmbh

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Indications & Clinical Uses

Irbesartan acts on the renin‑angiotensin‑aldosterone system to lower blood pressure and protect renal function.

  • Hypertension: lowers blood pressure and reduces cardiovascular risk.
  • Diabetic nephropathy: slows progression of kidney disease in patients with type 2 diabetes.
  • Essential hypertension: provides long‑term blood pressure control.

How It Works

  • Irbesartan selectively antagonizes angiotensin II type 1 (AT1) receptors on vascular smooth muscle and adrenal cells. By blocking these receptors, it prevents angiotensin II‑mediated vasoconstriction and aldosterone secretion, leading to vasodilation, reduced sodium and water retention, and ultimately lower systemic blood pressure and renal protection.

Side Effects

Common Side Effects

  • Dizziness: sensation of light‑headedness, especially after standing.
  • Headache: mild to moderate intensity.
  • Fatigue: feeling of tiredness or lack of energy.
  • Nausea: occasional upset stomach.
  • Upper respiratory infection: mild cold‑like symptoms.
  • Hyperkalemia: elevated potassium levels, usually mild.

Serious or Rare Side Effects

  • Angioedema: swelling of face, lips, tongue, or throat requiring immediate medical attention.
  • Severe hypotension: marked drop in blood pressure causing faintness or shock.
  • Acute renal failure: sudden loss of kidney function, especially in patients with pre‑existing renal disease.
  • Hepatic injury: abnormal liver enzymes or hepatitis.
  • Life‑threatening hyperkalemia: dangerously high potassium levels.
  • Anaphylactic reaction: rare but severe allergic response.

Precautions & Warnings

Irbesartan should be used with careful monitoring and consideration of patient‑specific factors.

  • Monitor blood pressure: check regularly to ensure therapeutic effect.
  • Assess renal function: evaluate serum creatinine and eGFR before and during treatment.
  • Check electrolytes: especially potassium levels to avoid hyperkalemia.
  • Avoid in severe hepatic impairment: consider alternative therapy.
  • Pregnancy: contraindicated in the second and third trimesters due to fetal risk.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Irbesartan may interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Concomitant use with aliskiren in diabetic patients: increased risk of renal impairment.
  • Potassium‑sparing diuretics or supplements: heightened risk of hyperkalemia.
  • ACE inhibitors: additive potassium increase and potential hypotension.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may diminish antihypertensive effect and affect renal function.
  • Lithium: possible increase in lithium serum concentrations.
  • Thiazide diuretics: may require dose adjustment of either agent.

Frequently Asked Questions

Irbesartan Stada is prescribed to treat high blood pressure (hypertension) and to slow the progression of kidney disease in patients with type 2 diabetes (diabetic nephropathy). By controlling blood pressure, it also helps reduce the risk of cardiovascular complications associated with these conditions.

Irbesartan works by selectively blocking angiotensin II type 1 (AT1) receptors. This inhibition prevents angiotensin II‑induced vasoconstriction and aldosterone release, leading to relaxed blood vessels, reduced sodium and water retention, and ultimately lower blood pressure and renal protection.

The specific dose of Irbesartan Stada is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and other factors. Patients should follow the dosage instructions provided by their healthcare professional and not adjust the dose on their own.

Irbesartan is generally contraindicated during the second and third trimesters of pregnancy because it may cause fetal harm. Safety during breastfeeding has not been established, so the medication should be used only if the potential benefit justifies the potential risk to the infant.

To place an order, submit an enquiry on the Irbesartan Stada product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

The primary alternative to Irbesartan is the ACE‑inhibitor class (e.g., enalapril). Both lower blood pressure by targeting the renin‑angiotensin system, but ARBs like Irbesartan are less likely to cause a persistent dry cough and have a lower incidence of angioedema, making them a preferred option for some patients.

Irbesartan tablets should be stored at ambient temperature, below 25 °C, in their original packaging to protect from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments.

Irbesartan is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water. Patients should follow the dosing schedule prescribed by their healthcare provider and not crush or split the tablet unless instructed.

Serious risks include angioedema (swelling of the face, lips, tongue, or throat), severe hypotension (dangerously low blood pressure), acute kidney injury, and significant hyperkalemia (high potassium levels). Patients should seek immediate medical attention if they experience any of these symptoms.

Irbesartan should not be used by individuals with known hypersensitivity to the drug or any of its components, patients with severe hepatic impairment, or women who are pregnant, especially in the second and third trimesters. Caution is also advised for patients with existing kidney disease or elevated potassium levels.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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