Product image of Irbesartan Teva (Irbesartan) supplied by GNH India

Irbesartan Teva

Active Ingredient:
Irbesartan
Origin:
EU

Irbesartan Teva (Irbesartan)

Irbesartan, the active ingredient in Irbesartan Teva, is an angiotensin II receptor blocker (ARB) presented as an oral tablet for oral use. It is employed to treat high blood pressure, protect kidney function in diabetes, and manage heart failure in adult patients, and improve cardiovascular outcomes as part of a comprehensive antihypertensive regimen.

GNH India supplies Irbesartan Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with reliable quality assurance and on‑time delivery across multiple regulatory regions.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Irbesartan, an angiotensin II receptor blocker, acts on the renin‑angiotensin system to lower blood pressure and protect target organs.

  • Hypertension: reduces systemic vascular resistance and lowers blood pressure in patients with essential hypertension.
  • Diabetic nephropathy: slows progression of kidney damage in patients with type 2 diabetes.
  • Heart failure: improves symptoms and reduces hospitalizations in patients with chronic heart failure.

How It Works

  • Irbesartan selectively blocks angiotensin II type 1 (AT1) receptors on vascular smooth muscle, adrenal gland, and renal tubular cells. By preventing angiotensin II binding, it inhibits vasoconstriction, aldosterone secretion, and sympathetic activation, leading to vasodilation, reduced sodium and water retention, and lowered blood pressure. The blockade also mitigates remodeling processes in the heart and kidneys and improves endothelial function, contributing to cardiovascular protection.

Side Effects

Irbesartan may cause a range of adverse reactions, varying in frequency and severity.

Common Side Effects

  • Dizziness: sensation of light‑headedness, especially after standing.
  • Headache: mild to moderate pain in the head region.
  • Fatigue: feeling unusually tired or weak.
  • Hyperkalemia: elevated blood potassium levels detectable on lab tests.

Serious or Rare Side Effects

  • Angioedema: swelling of the face, lips, tongue or throat that may impair breathing.
  • Severe hypotension: marked drop in blood pressure causing fainting or shock.
  • Renal impairment: worsening kidney function, particularly in patients with pre‑existing disease.

Precautions & Warnings

When prescribing Irbesartan, clinicians should consider several safety measures and patient‑specific factors.

  • Monitor blood pressure: check regularly to ensure therapeutic response and avoid excessive hypotension.
  • Assess renal function: evaluate serum creatinine and eGFR before initiation and during therapy.
  • Check serum potassium: periodic testing is advised to detect hyperkalemia.
  • Avoid use in patients with bilateral renal artery stenosis: risk of renal failure may increase.
  • Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture and light.

Avoid Interactions

Irbesartan can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Potassium‑sparing diuretics or supplements: may cause dangerous hyperkalemia.
  • ACE inhibitors or other ARBs: concurrent use increases risk of hypotension, renal dysfunction, and hyperkalemia.
  • Aliskiren in diabetic patients: combined use can lead to renal impairment and hyperkalemia.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may reduce antihypertensive effect and affect kidney function.
  • Lithium: increased lithium levels can cause toxicity.
  • Diuretics (especially thiazides): may enhance potassium loss, requiring electrolyte monitoring.

Frequently Asked Questions

Irbesartan Teva is indicated for the treatment of essential hypertension, for slowing the progression of diabetic nephropathy in patients with type 2 diabetes, and for managing chronic heart failure. These uses reflect its role as an angiotensin II receptor blocker that lowers blood pressure and protects target organs.

Irbesartan works by selectively blocking angiotensin II type 1 (AT1) receptors on blood vessels, the adrenal gland, and renal tubular cells. This inhibition prevents angiotensin II‑mediated vasoconstriction and aldosterone release, resulting in vasodilation, reduced sodium and water retention, and lower systemic blood pressure.

The appropriate dose of Irbesartan Teva is determined by the prescribing healthcare professional based on the individual’s medical condition, response to therapy, and renal function. Dosage adjustments may be required for specific patient populations, and the prescriber will provide the exact regimen.

The safety of Irbesartan during pregnancy and lactation has not been established. It is generally contraindicated in pregnancy because of potential fetal toxicity, and caution is advised for nursing mothers. Physicians should evaluate risks and consider alternative therapies when treating pregnant or breastfeeding patients.

To order Irbesartan Teva, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Irbesartan belongs to the ARB class, offering blood‑pressure reduction similar to ACE inhibitors but with a lower incidence of cough and angioedema. Compared with calcium‑channel blockers or diuretics, ARBs provide additional renal‑protective benefits, especially in diabetic patients, making them a preferred option in certain clinical scenarios.

Irbesartan tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original container, protect from moisture and direct light, and ensure the packaging remains tightly closed until use. Do not store in a refrigerator or freezer.

Irbesartan Teva is taken orally, usually once daily. The tablet can be swallowed with or without food, according to the prescriber’s instructions. Patients should follow the dosing schedule provided by their healthcare professional and not alter the regimen without medical advice.

Serious adverse events associated with Irbesartan include angioedema (swelling of the face, lips, tongue, or throat), severe hypotension (dangerously low blood pressure), hyperkalemia (elevated potassium levels), and worsening renal function, particularly in patients with pre‑existing kidney disease.

Irbesartan is contraindicated in patients with known bilateral renal artery stenosis, those who are pregnant, or individuals with a history of hypersensitivity to the drug. Caution is also advised for patients with severe hepatic impairment or uncontrolled hyperkalemia, and the medication should be avoided in these groups.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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