Product image of Irbesartan Teva (Irbesartan) supplied by GNH India

Irbesartan Teva

Active Ingredient:
Irbesartan
Origin:
EU

Irbesartan Teva (Irbesartan)

Irbesartan, the active ingredient in Irbesartan Teva, is a Angiotensin II receptor blocker (ARB) presented as an oral dosage form for oral use. It is employed to manage high blood pressure and to protect kidney function in patients with diabetic nephropathy.

GNH India supplies Irbesartan Teva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Irbesartan Teva belongs to the Angiotensin II receptor blocker class and is used to treat conditions related to the renin‑angiotensin system.

  • Hypertension: lowers systemic blood pressure and reduces cardiovascular risk.
  • Diabetic nephropathy: slows the progression of kidney damage in patients with type 2 diabetes.

How It Works

  • Irbesartan selectively blocks angiotensin II type 1 (AT1) receptors, preventing angiotensin II from causing vasoconstriction and aldosterone release. This inhibition leads to relaxation of blood vessels, reduced peripheral resistance, and decreased sodium and water retention, thereby lowering blood pressure and protecting renal function.

Side Effects

Irbesartan may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Dizziness: feeling light‑headed, especially after standing.
  • Headache: mild to moderate pain in the head region.
  • Fatigue: unusual tiredness or lack of energy.

Serious or Rare Side Effects

  • Angioedema: swelling of the face, lips, tongue or throat that may impair breathing.
  • Severe hypotension: markedly low blood pressure causing fainting.
  • Acute kidney injury: sudden decline in renal function.
  • Hyperkalemia: elevated blood potassium that can affect heart rhythm.
  • Liver enzyme elevation: increased hepatic transaminases indicating liver stress.
  • Neutropenia: reduced white blood cell count increasing infection risk.

Precautions & Warnings

Before initiating therapy with Irbesartan, several safety considerations should be observed.

  • Blood pressure monitoring: check regularly to avoid excessive hypotension.
  • Renal function assessment: evaluate serum creatinine and eGFR before and during treatment.
  • Serum potassium: monitor for hyperkalemia, especially when combined with potassium‑sparing agents.
  • Hepatic impairment: use caution in patients with liver disease as metabolism may be altered.
  • Hypersensitivity: discontinue if signs of allergic reaction such as rash or swelling appear.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Irbesartan can interact with several drug classes, influencing safety or efficacy.

Major Interactions (Avoid)

  • Aliskiren in diabetic patients: combined use increases risk of renal impairment and hyperkalemia.
  • Potassium‑sparing diuretics or supplements: may cause dangerous elevations in serum potassium.
  • ACE inhibitors: concurrent use raises the likelihood of angioedema.

Moderate Interactions (Monitor Closely)

  • NSAIDs: can blunt antihypertensive effect and affect renal function.
  • Lithium: may increase lithium concentrations, leading to toxicity.
  • Cyclosporine: can exacerbate renal dysfunction when used together.

Frequently Asked Questions

Irbesartan Teva is prescribed to lower high blood pressure (hypertension) and to slow the progression of kidney disease in patients with type 2 diabetes (diabetic nephropathy). By controlling these conditions, it helps reduce the risk of cardiovascular events and renal failure.

Irbesartan blocks the angiotensin II type 1 (AT1) receptors, preventing angiotensin II from causing blood vessel constriction and aldosterone release. This results in vasodilation, reduced sodium and water retention, and ultimately lower blood pressure and renal protection.

The dose of Irbesartan Teva is individualized by the prescribing healthcare professional based on the patient’s blood pressure, kidney function, and overall health status. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of Irbesartan in pregnancy has not been established and the drug is generally avoided because it may harm the developing fetus. Limited data exist for breastfeeding; therefore, use is usually discouraged unless the benefits outweigh potential risks.

To order Irbesartan Teva, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Irbesartan shares the same mechanism as other ARBs, offering effective blood‑pressure control with a lower incidence of cough compared with ACE inhibitors. Compared with some ARBs, it has a favorable renal‑protective profile in diabetic nephropathy, but individual response may vary, so clinicians choose based on patient tolerance and comorbidities.

Irbesartan Teva should be stored at ambient temperature, below 25 °C, in its original packaging to protect from moisture and light. Keep the product out of reach of children and do not use it after the expiration date printed on the label.

Irbesartan Teva is taken orally, usually once daily, with or without food. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed by a healthcare professional.

Serious adverse events include angioedema (swelling of the face, lips, tongue, or throat), severe hypotension, acute kidney injury, marked hyperkalemia that can cause cardiac arrhythmias, and significant liver enzyme elevations. Patients should seek immediate medical attention if any of these symptoms occur.

Irbesartan Teva is contraindicated in individuals with known hypersensitivity to irbesartan or any ARB components, those with severe renal impairment, and pregnant women. Caution is also advised for patients with hepatic disease, electrolyte disturbances, or those taking medications that raise potassium levels.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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