Product image of Iridina Infezioni E Infiammazioni (Dexamethasone, Tobramycin) supplied by GNH India

Iridina Infezioni E Infiammazioni

Active Ingredient:
Dexamethasone, Tobramycin
Origin:
EU

Iridina Infezioni E Infiammazioni (Dexamethasone, Tobramycin)

Dexamethasone/Tobramycin, the active ingredient in Iridina Infezioni E Infiammazioni, is a corticosteroid/aminoglycoside antibiotic presented as an ophthalmic preparation for ocular use. It treats bacterial conjunctivitis, ocular inflammation, keratitis and post‑surgical eye inflammation in patients of all ages as directed by a healthcare professional.

GNH India supplies Iridina Infezioni E Infiammazioni as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution through its experienced network of partners.

Manufacturer / TM Owner

Montefarmaco Otc S.P.A.

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Indications & Clinical Uses

Iridina Infezioni E Infiammazioni combines a corticosteroid and an aminoglycoside antibiotic to address bacterial eye infections and inflammatory conditions.

  • Bacterial conjunctivitis: reduces bacterial load and alleviates redness, discharge and discomfort.
  • Ocular inflammation (e.g., uveitis, postoperative inflammation): suppresses inflammatory mediators to decrease swelling and pain.
  • Keratitis: provides antibacterial activity while controlling corneal inflammation.
  • Post‑surgical eye inflammation: prevents infection and controls postoperative swelling after ocular surgery.

How It Works

  • Dexamethasone binds to intracellular glucocorticoid receptors in ocular tissues, modulating gene transcription and inhibiting the release of prostaglandins, cytokines and other inflammatory mediators, thereby reducing ocular inflammation and edema. Tobramycin, delivered as a topical ophthalmic solution, attaches to the bacterial 30S ribosomal subunit, interfering with protein synthesis and leading to rapid bactericidal activity against susceptible Gram‑negative and some Gram‑positive organisms.

Side Effects

The ocular formulation may cause local adverse reactions, ranging from mild to serious.

Common Side Effects

  • Eye irritation or burning sensation.
  • Temporary blurred vision.
  • Increased intraocular pressure.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis) with eyelid swelling.
  • Corneal ulceration or perforation.
  • Vision loss.

Precautions & Warnings

When using Iridina Infezioni E Infiammazioni, consider the following precautions to ensure safe and effective therapy.

  • Pregnancy: safety not established; use only if clearly needed.
  • Breastfeeding: unknown; weigh potential risks and benefits.
  • Contact lens wearers: avoid using the drops while lenses are in place.
  • Pre‑existing glaucoma or ocular hypertension: monitor intraocular pressure closely.
  • Systemic corticosteroid therapy: may increase risk of systemic glucocorticoid effects.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Iridina Infezioni E Infiammazioni may interact with other ophthalmic or systemic agents.

Major Interactions (Avoid)

  • Systemic corticosteroids: additive glucocorticoid effects may increase systemic exposure.
  • Other ophthalmic antibiotics: risk of antagonistic activity or toxicity.
  • Anticholinergic eye drops: may reduce the anti‑inflammatory efficacy.
  • Non‑steroidal anti‑inflammatory eye drops: increased risk of ocular irritation.

Moderate Interactions (Monitor Closely)

  • Topical beta‑blocker eye drops: may mask changes in intraocular pressure.
  • Antifungal eye preparations: possible reduced antifungal efficacy.
  • Systemic aminoglycosides: potential additive ototoxicity if systemic absorption occurs.

Frequently Asked Questions

Iridina Infezioni E Infiammazioni is an ophthalmic solution that combines a corticosteroid with an aminoglycoside antibiotic. It is indicated for the treatment of bacterial conjunctivitis, ocular inflammation such as uveitis or postoperative inflammation, keratitis, and for preventing infection after eye surgery.

Dexamethasone acts as a glucocorticoid receptor agonist, suppressing the production of inflammatory mediators in ocular tissues. Tobramycin binds to the bacterial 30S ribosomal subunit, disrupting protein synthesis and causing rapid bacterial cell death. Together they reduce inflammation and eliminate infection.

The dosing regimen for Iridina Infezioni E Infiammazioni is determined by the prescribing clinician based on the specific condition, severity, and patient characteristics. The prescriber will provide instructions on the number of drops, frequency, and duration of therapy.

Safety data for dexamethasone/tobramycin ophthalmic use during pregnancy and lactation are limited. The product should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.

To place an order, submit an enquiry on the Iridina Infezioni E Infiammazioni product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Iridina combines a potent corticosteroid (dexamethasone) with a broad‑spectrum aminoglycoside (tobramycin) in a single formulation, offering both anti‑inflammatory and antibacterial activity. Compared with separate eye drops, it simplifies dosing and may improve patient compliance, while providing coverage against many common ocular pathogens.

Store the ophthalmic solution at room temperature, preferably below 25 °C. Keep the bottle tightly closed in its original packaging, protect it from direct light and moisture, and discard any product that appears discolored or contains particles.

The medication is applied as eye drops. The patient should wash their hands, tilt the head back, pull down the lower eyelid, and instill the prescribed number of drops into the conjunctival sac. The eye should be closed gently for a few seconds to allow absorption.

Serious adverse events include severe allergic reactions such as anaphylaxis, corneal ulceration or perforation, and a significant rise in intraocular pressure that could lead to glaucoma or vision loss. Any sudden worsening of vision, eye pain, or swelling should prompt immediate medical attention.

Patients with known hypersensitivity to dexamethasone, tobramycin, or any component of the formulation should avoid the product. It is also contraindicated in individuals with viral eye infections such as herpes simplex keratitis, as corticosteroids may exacerbate the condition.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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