Product image of Irireos Antistaminico (Cetirizine Dihydrochloride) supplied by GNH India

Irireos Antistaminico

Active Ingredient:
Cetirizine Dihydrochloride
Origin:
EU

Irireos Antistaminico (Cetirizine Dihydrochloride)

Cetirizine, the active ingredient in Irireos Antistaminico, is an antihistamine presented as an oral tablet for oral use. It relieves symptoms of allergic rhinitis and urticaria in adults and children.

GNH India supplies Irireos Antistaminico as a licensed, GDP-compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Montefarmaco Otc S.P.A.

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Indications & Clinical Uses

Irireos Antistaminico, a selective H1‑receptor antagonist, is used to manage allergic conditions.

  • Allergic rhinitis: reduces nasal congestion, sneezing, itching and watery discharge.
  • Urticaria: alleviates hives and associated itching.
  • Seasonal allergy: helps control symptoms triggered by pollen or other environmental allergens.

How It Works

  • Cetirizine dihydrochloride acts as a selective antagonist of peripheral H1 histamine receptors. By blocking these receptors, it prevents histamine‑induced vasodilation, increased vascular permeability, and sensory nerve stimulation, thereby reducing the classic signs of allergic reactions such as itching, swelling, and rhinorrhea.

Side Effects

Common Side Effects

  • Drowsiness: mild to moderate sleepiness.
  • Headache: transient cranial discomfort.
  • Dry mouth: reduced salivation.
  • Fatigue: general lack of energy.
  • Nausea: occasional stomach upset.
  • Dizziness: brief sense of light‑headedness.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Stevens‑Johnson syndrome: rare but serious skin disorder.
  • Liver enzyme elevation: possible hepatic involvement.
  • Blood dyscrasias: abnormal blood cell counts.
  • Severe skin reactions: such as toxic epidermal necrolysis.
  • Cardiovascular effects: rare arrhythmias or palpitations.

Precautions & Warnings

Irireos Antistaminico should be used with caution in certain populations and conditions.

  • Pregnancy: consult a healthcare provider before use.
  • Breastfeeding: consider potential exposure to the infant.
  • Elderly: monitor for increased sedation or confusion.
  • Renal impairment: dose adjustment may be required.
  • Drug interactions: review concomitant medications for additive effects.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Cetirizine may interact with several drug classes.

Major Interactions (Avoid)

  • Alcohol: may increase sedation and impair coordination.
  • Central nervous system depressants: additive drowsiness risk.
  • Theophylline: may raise plasma theophylline concentrations.

Moderate Interactions (Monitor Closely)

  • Ketoconazole and other azole antifungals: can increase cetirizine levels.
  • Ritonavir: may elevate cetirizine exposure.
  • Diphenhydramine: combined antihistaminic effect may enhance sedation.

Frequently Asked Questions

Irireos Antistaminico contains cetirizine, an H1‑receptor antagonist that is used to relieve symptoms of allergic rhinitis, such as sneezing and nasal congestion, and to treat urticaria (hives) by reducing itching and skin swelling.

Cetirizine works by selectively blocking peripheral H1 histamine receptors. This inhibition prevents histamine from binding to its receptors, thereby reducing the vascular and sensory effects that cause itching, swelling, and nasal discharge during allergic reactions.

The appropriate dose of Irireos Antistaminico is determined by a qualified healthcare professional based on the patient’s age, weight, renal function, and the severity of symptoms. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety in pregnancy and lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss the risks and benefits with their healthcare provider before using Irireos Antistaminico.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Irireos Antistaminico (cetirizine) is a second‑generation antihistamine that typically causes less sedation than first‑generation agents like diphenhydramine. It offers a rapid onset of action and a once‑daily dosing schedule, making it convenient for managing allergic symptoms.

Store Irireos Antistaminico at ambient temperature below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Irireos Antistaminico is taken orally, usually with a glass of water. It can be taken with or without food, but patients should follow the specific instructions provided by their prescriber.

Serious adverse reactions, although rare, include anaphylaxis, severe skin reactions such as Stevens‑Johnson syndrome, and significant liver enzyme elevations. Patients should seek immediate medical attention if they experience symptoms like rash, swelling, difficulty breathing, or jaundice.

Individuals with known hypersensitivity to cetirizine or any component of the formulation should avoid using Irireos Antistaminico. Caution is also advised for patients with severe renal impairment, as dose adjustment may be required.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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