Product image of Ironcrose (Iron) supplied by GNH India

Ironcrose

Active Ingredient:
Iron
Origin:
EU

Ironcrose (Iron)

Iron, the active ingredient in Ironcrose, is an iron supplement presented as an intravenous solution for intravenous use. It treats iron deficiency anemia and anemia associated with chronic kidney disease by delivering elemental iron directly into the bloodstream. The formulation is designed for rapid repletion of iron stores in patients who cannot tolerate or absorb oral iron preparations.

GNH India supplies Ironcrose as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution.

Manufacturer / TM Owner

Target Pharma Single Member Private Ltd

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Indications & Clinical Uses

Ironcrose is used to treat conditions related to iron deficiency and is administered intravenously to replenish iron stores.

  • Iron deficiency anemia: restores hemoglobin levels and replenishes depleted iron stores in patients with insufficient dietary or absorptive iron.
  • Anemia of chronic kidney disease: provides elemental iron to support erythropoiesis in patients receiving dialysis or renal replacement therapy.

How It Works

  • Ironcrose consists of a stable iron‑carbohydrate complex that releases elemental iron after intravenous infusion. The iron is taken up by reticulo‑endothelial cells, incorporated into ferritin, and subsequently transferred to transferrin for delivery to the bone marrow, where it supports hemoglobin synthesis and restores depleted iron reserves. The controlled release minimizes free iron and reduces oxidative stress.

Side Effects

Intravenous ironcrose may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea
  • Headache
  • Muscle cramps
  • Injection site pain or erythema
  • Hypotension or dizziness
  • Metallic taste

Serious or Rare Side Effects

  • Anaphylactic or severe hypersensitivity reactions
  • Acute hypotensive shock
  • Acute respiratory distress syndrome
  • Hemolysis
  • Severe hypertension
  • Cardiac arrest

Precautions & Warnings

When using ironcrose, clinicians should observe several safety measures to minimize risks.

  • Assess iron status: confirm iron deficiency before initiating therapy.
  • Monitor laboratory values: check hemoglobin, ferritin and transferrin saturation during treatment.
  • Use under medical supervision: administer only by trained healthcare professionals.
  • Avoid in known hypersensitivity: do not give to patients with previous reactions to iron‑carbohydrate complexes.
  • Caution in active infection: defer infusion until infection is controlled.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Ironcrose can interact with other medicines, affecting its safety or efficacy.

Major Interactions (Avoid)

  • Other intravenous iron products: concurrent use may cause iron overload and severe reactions.
  • Known hypersensitivity to dextran or other iron complexes: increases risk of anaphylaxis.

Moderate Interactions (Monitor Closely)

  • High‑dose vitamin C or other antioxidants: may increase free iron and oxidative stress.
  • Erythropoiesis‑stimulating agents: combined use can raise blood pressure.
  • Iron chelators (e.g., deferoxamine): may reduce the effectiveness of ironcrose.
  • Antacids containing aluminum or magnesium: may interfere with iron binding if given simultaneously.

Frequently Asked Questions

Ironcrose is an intravenous iron preparation used to treat iron deficiency anemia and anemia associated with chronic kidney disease. It provides elemental iron directly into the bloodstream, helping to restore hemoglobin levels and replenish depleted iron stores when oral iron is ineffective or not tolerated.

Ironcrose delivers a stable iron‑carbohydrate complex that releases elemental iron after infusion. The iron is captured by reticulo‑endothelial cells, stored as ferritin, and later transferred to transferrin for transport to the bone marrow, where it supports hemoglobin synthesis and red blood cell production.

The dose of Ironcrose is individualized based on the patient’s iron deficit, hemoglobin level, body weight and clinical condition. The prescribing clinician determines the total iron requirement and the infusion schedule, which may be given as a single dose or divided over several sessions.

Safety data for Ironcrose in pregnancy and lactation are limited. It should be used only if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To order Ironcrose, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required) and necessary import documentation.

Ironcrose is a low‑molecular‑weight iron‑carbohydrate complex that releases iron more gradually than some high‑molecular‑weight formulations, resulting in a lower incidence of acute hypersensitivity reactions. Compared with ferric gluconate or iron sucrose, it offers similar efficacy for hemoglobin correction but may differ in dosing frequency and infusion time.

Ironcrose must be stored at 2‑8 °C (refrigerated). Keep the vials in their original packaging, protect them from light, and do not freeze or shake the solution. Before administration, allow the product to reach room temperature if required by the specific preparation instructions.

Ironcrose is administered by intravenous infusion, typically through a peripheral or central venous line. The infusion rate and total volume are determined by the prescriber and may be adjusted based on patient tolerance. Monitoring of vital signs during and after the infusion is recommended.

The most serious risks include severe hypersensitivity reactions such as anaphylaxis, acute hypotensive shock, and rare events like acute respiratory distress syndrome or hemolysis. Prompt recognition and immediate medical intervention are essential if any signs of a severe reaction occur during or after infusion.

Ironcrose should be avoided in patients with known hypersensitivity to iron‑carbohydrate complexes, those who have experienced previous severe reactions to any intravenous iron product, and individuals with active, uncontrolled infections where iron supplementation could exacerbate the condition.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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