Product image of Isodex (Glucose Monohydrate) supplied by GNH India

Isodex

Active Ingredient:
Glucose Monohydrate
Origin:
EU

Isodex (Glucose Monohydrate)

Glucose Monohydrate, the active ingredient in Isodex, is an excipient presented as an intravenous solution for intravenous use. It provides a source of carbohydrate and energy in clinical settings such as hypoglycemia management and parenteral nutrition.

GNH India supplies Isodex as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

Manufacturer / TM Owner

Teva Gyógyszergyár Zrt

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Indications & Clinical Uses

Isodex (glucose monohydrate) is used as an intravenous carbohydrate source in metabolic and nutritional support contexts.

  • Hypoglycemia: restores blood glucose levels in patients with low blood sugar.
  • Parenteral nutrition: supplies carbohydrate calories as part of total nutrient admixtures.
  • Intraoperative fluid management: provides an isotonic glucose solution for fluid replacement during surgery.
  • Electrolyte balance: serves as a carrier for electrolytes in IV therapy.

How It Works

  • Glucose monohydrate delivered intravenously enters the bloodstream and is taken up by cells via glucose transporters. It is metabolized through glycolysis to generate ATP, thereby raising plasma glucose concentrations and providing immediate energy for cellular processes. The solution also serves as an isotonic carrier for compatible electrolytes and medications.

Side Effects

Common Side Effects

  • Hyperglycemia: elevated blood glucose levels.
  • Local irritation: pain or redness at infusion site.
  • Electrolyte disturbance: shifts in sodium or potassium balance.
  • Fluid overload: excessive volume leading to edema.

Serious or Rare Side Effects

  • Severe hyperglycemia leading to ketoacidosis.
  • Allergic reaction: rash, urticaria, or anaphylaxis.
  • Infection risk: contamination of the IV solution.
  • Hypotension: rapid infusion causing a drop in blood pressure.

Precautions & Warnings

Isodex should be administered with careful clinical oversight.

  • Patient assessment: check baseline blood glucose before infusion.
  • Infusion rate: follow guidelines to avoid rapid glucose spikes.
  • Compatibility: verify compatibility with other IV drugs before mixing.
  • Monitoring: observe for signs of hyperglycemia and fluid overload during administration.
  • Special populations: adjust usage in renal or cardiac impairment.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Glucose monohydrate may interact with other therapies.

Major Interactions (Avoid)

  • Insulin therapy: concurrent high-dose glucose can counteract insulin effects.
  • Sodium bicarbonate solutions: may precipitate when mixed with glucose solutions.

Moderate Interactions (Monitor Closely)

  • Diuretics: can alter fluid balance when combined with glucose solutions.
  • Beta‑blockers: may mask hypoglycemia symptoms.
  • Calcium‑containing solutions: monitor for calcium‑phosphate precipitation.

Frequently Asked Questions

Isodex contains glucose monohydrate and is used as an intravenous carbohydrate source. It helps restore blood glucose in hypoglycemia, provides calories in parenteral nutrition, and can serve as an isotonic carrier for compatible electrolytes during IV therapy.

When administered intravenously, glucose monohydrate enters the bloodstream and is taken up by cells via glucose transporters. It is metabolized through glycolysis, producing ATP and raising plasma glucose levels, which supplies immediate energy for cellular functions.

The dose of Isodex is determined by the prescribing clinician based on the patient’s clinical condition, blood glucose level, and overall fluid management plan. Specific dosing regimens are not provided here and should follow medical guidance.

Glucose monohydrate is a basic carbohydrate that may be used when clinically indicated during pregnancy or lactation, but the decision rests with the treating physician. Safety information should be reviewed with a healthcare professional.

To order Isodex, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Isodex provides glucose monohydrate in a sterile, ready‑to‑use intravenous solution, similar to other glucose IV products. Differences may lie in formulation purity, packaging, and regulatory status. Clinicians should compare specifications, compatibility data, and supplier reliability when selecting a product.

Isodex should be stored at ambient temperature, protected from moisture and direct sunlight, and kept in its original sealed container. Avoid freezing the solution and ensure the vial is inspected for integrity before use.

Isodex is administered intravenously, typically via a peripheral or central line. The infusion rate and volume are set according to the patient’s clinical needs and monitoring parameters, following standard aseptic techniques.

Serious risks include severe hyperglycemia that can lead to ketoacidosis, allergic reactions such as anaphylaxis, infection from contaminated solutions, and fluid overload causing edema or pulmonary congestion. Continuous monitoring is essential during administration.

Isodex should be avoided in patients with known hypersensitivity to glucose monohydrate, uncontrolled hyperglycemia, or conditions where fluid overload is a concern, such as severe heart failure, unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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