Product image of Isofundine (Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Mal) supplied by GNH India

Isofundine

Active Ingredient:
Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Mal
Origin:
EU

Isofundine (Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Mal)

Magnesium chloride hexahydrate, potassium chloride, sodium chloride, calcium chloride dihydrate and malate, the active ingredients in Isofundine, are an electrolyte solution presented as an injectable solution for intravenous use. It restores electrolyte balance and plasma volume in patients with electrolyte depletion, such as hypokalemia, hyponatremia, hypocalcemia, and magnesium deficiency.

GNH India supplies Isofundine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Isofundine is used to correct electrolyte disturbances and support fluid replacement in clinical settings.

  • Electrolyte depletion: restores normal levels of magnesium, potassium, sodium, and calcium.
  • Hypokalemia: increases serum potassium concentration.
  • Hyponatremia: raises plasma sodium concentration.
  • Hypocalcemia: supplies calcium ions to correct low calcium.
  • Magnesium deficiency: provides magnesium to normalize serum levels.
  • Fluid replacement: contributes to plasma volume expansion in patients requiring volume resuscitation.

How It Works

  • Isofundine delivers magnesium, potassium, sodium, and calcium ions directly into the bloodstream via intravenous infusion. The supplied ions replace those lost through renal excretion, gastrointestinal loss, or cellular shifts, thereby re‑establishing osmotic balance, membrane potential, and enzymatic activity. The resulting increase in plasma electrolyte concentrations expands intravascular volume and supports normal cellular function.

Side Effects

Isofundine may be associated with adverse reactions typical of intravenous electrolyte solutions.

Common Side Effects

  • Injection site pain: mild discomfort at the infusion site.
  • Hypernatremia: elevated sodium levels if administered excessively.
  • Hyperkalemia: increased potassium concentration leading to cardiac effects.
  • Hypercalcemia: raised calcium levels causing muscle weakness or arrhythmia.
  • Hypermagnesemia: excess magnesium resulting in hypotension or flushing.

Serious or Rare Side Effects

  • Cardiac arrhythmia: abnormal heart rhythm due to electrolyte imbalance.
  • Severe hypotension: marked drop in blood pressure.
  • Allergic reaction: rash, itching, or anaphylaxis.
  • Metabolic alkalosis: shift in acid‑base balance.
  • Vascular thrombosis: clot formation at catheter site.

Precautions & Warnings

When using Isofundine, clinicians should observe specific precautions to minimize risks.

  • Renal impairment: adjust infusion rate and monitor serum electrolytes closely.
  • Cardiac disease: avoid rapid infusion that may provoke arrhythmias.
  • Fluid overload: assess volume status to prevent pulmonary edema.
  • Electrolyte monitoring: check serum levels before, during, and after administration.
  • Drug incompatibility: do not mix with calcium‑containing solutions unless compatibility is confirmed.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Isofundine can interact with other medications that affect electrolyte balance or cardiac conduction.

Major Interactions (Avoid)

  • Digoxin: increased risk of toxicity due to altered potassium levels.
  • Calcium channel blockers: additive effects on cardiac conduction when calcium levels rise.
  • Loop diuretics: may cause excessive electrolyte shifts if given concurrently.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors/ARBs: monitor potassium to avoid hyperkalemia.
  • Beta‑blockers: watch for bradycardia if electrolyte disturbances occur.
  • Antacids containing magnesium or calcium: may increase total electrolyte load.

Frequently Asked Questions

Isofundine is an intravenous electrolyte solution used to treat electrolyte depletion and to replace fluids in patients with conditions such as hypokalemia, hyponatremia, hypocalcemia, magnesium deficiency, and in situations where plasma volume expansion is required.

The formulation provides magnesium, potassium, sodium, and calcium ions directly into the bloodstream. These ions replenish those lost from the body, restore osmotic and electrical balance, support enzymatic reactions, and expand intravascular volume, thereby normalising cellular and systemic functions.

The dose of Isofundine is determined by the prescribing clinician based on the patient’s electrolyte deficits, fluid status, and clinical condition. Dosage calculations consider laboratory values, body weight, and the intended rate of correction.

Safety data for Isofundine in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.

To order Isofundine, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Isofundine contains a balanced mix of magnesium, potassium, sodium, and calcium, whereas many standard solutions such as normal saline or lactated Ringer’s lack magnesium and potassium. This broader ion profile can be advantageous when multiple electrolyte deficits need simultaneous correction.

Isofundine should be stored at 2‑8 °C, protected from light, and kept in its original container. Do not freeze or shake the solution. Before use, inspect for particulate matter and ensure the vial is within its expiry date.

Isofundine is supplied as a sterile solution for injection and is administered intravenously. The infusion rate and total volume are set by the healthcare professional according to the patient’s electrolyte and fluid needs, typically using an infusion pump or controlled drip.

Serious risks include cardiac arrhythmias, severe hypotension, allergic reactions such as anaphylaxis, metabolic alkalosis, and vascular thrombosis at the catheter site. Prompt monitoring of cardiac rhythm and blood pressure is essential during and after infusion.

Isofundine is contraindicated in patients with known hypersensitivity to any of its components, in those with uncontrolled hyperkalemia, hypercalcemia, or hypermagnesemia, and in individuals with severe fluid overload where additional volume could worsen pulmonary edema.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Mal

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT