Product image of Isogel (Ispaghula Husk) supplied by GNH India

Isogel

Active Ingredient:
Ispaghula Husk
Origin:
EU

Isogel (Ispaghula Husk)

Ispaghula husk, the active ingredient in Isogel, is a bulk-forming laxative presented as an oral formulation for oral use. It is used to increase stool bulk and water content, facilitating intestinal transit and relieving constipation in adults.

GNH India supplies Isogel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Soho Flordis Uk Limited

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Indications & Clinical Uses

Isogel is a bulk‑forming laxative that acts on the gastrointestinal tract to improve stool consistency and promote regularity.

  • Constipation: softens stool and encourages regular bowel movements.
  • Irritable bowel syndrome (symptom relief): reduces abdominal discomfort by normalising stool form.
  • Bowel irregularity: helps establish a predictable bowel pattern in occasional irregularity.

How It Works

  • Ispaghula husk consists of soluble dietary fiber that absorbs water in the intestinal lumen, forming a viscous gel. This gel increases stool bulk, stimulates stretch receptors in the colon, and accelerates peristaltic activity, thereby enhancing intestinal transit and easing the passage of feces without systemic absorption.

Side Effects

Isogel may cause mild, transient reactions related to its fiber content.

Common Side Effects

  • Abdominal bloating
  • Flatulence
  • Mild abdominal cramps
  • Nausea
  • Increased stool frequency
  • Loose stools or mild diarrhea

Serious or Rare Side Effects

  • Intestinal obstruction or impaction
  • Severe abdominal pain
  • Allergic reaction (rash, itching, swelling)
  • Rectal bleeding

Precautions & Warnings

Before using Isogel, consider the following safety measures.

  • Fluid intake: ensure adequate water consumption to prevent dehydration.
  • Dosage: do not exceed the amount recommended by a healthcare professional.
  • Pre‑existing conditions: avoid use in patients with known bowel obstruction or severe constipation.
  • Drug interactions: inform the prescriber of any concurrent medications, especially those affecting gastrointestinal motility.
  • Allergies: discontinue if signs of hypersensitivity appear.

Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ispaghula husk can affect the absorption of certain medicines.

Major Interactions (Avoid)

  • Anticholinergic agents: may reduce laxative efficacy.
  • Mineral oil: can interfere with fiber’s water‑binding capacity.
  • Opioid analgesics: may exacerbate constipation, diminishing overall benefit.

Moderate Interactions (Monitor Closely)

  • Iron supplements: fiber may decrease iron absorption.
  • Calcium or multivitamin tablets: take at least 2 hours apart.
  • Tetracycline antibiotics: fiber may reduce drug bioavailability.

Frequently Asked Questions

Isogel is an oral bulk‑forming laxative indicated for the relief of occasional constipation and for symptom management in irritable bowel syndrome. By increasing stool bulk and water content, it helps promote regular bowel movements and reduces abdominal discomfort associated with irregular bowel habits.

Ispaghula husk is a soluble dietary fiber that absorbs water in the gut, forming a gel‑like mass. This mass enlarges the stool, stimulates stretch receptors in the colon, and enhances peristaltic activity, thereby facilitating smoother transit of feces through the intestines.

The appropriate dose of Isogel is determined by the prescribing healthcare professional based on the individual’s age, condition severity, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

Safety data for Ispaghula husk during pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using Isogel to weigh potential benefits against any unknown risks.

To place an order, submit an enquiry on the Isogel product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Isogel belongs to the bulk‑forming laxative class, similar to psyllium or methylcellulose. Unlike stimulant laxatives, it works locally by adding fiber and water to stool, offering a gentler, non‑systemic option with a lower risk of electrolyte imbalance, making it suitable for long‑term use under medical supervision.

Isogel should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, excessive heat, and direct sunlight to maintain its efficacy and prevent clumping of the fiber.

Isogel is taken orally, typically mixed with a full glass of water or another suitable fluid. The mixture should be consumed immediately after preparation to ensure the fiber expands properly and provides the intended laxative effect.

Serious risks, though uncommon, include intestinal obstruction or impaction, severe abdominal pain, allergic reactions such as rash or swelling, and rectal bleeding. Patients experiencing any of these symptoms should discontinue use and seek medical attention promptly.

Isogel is contraindicated in individuals with known or suspected bowel obstruction, severe constipation, chronic intestinal diseases that impair motility, or a documented hypersensitivity to Ispaghula husk or any excipients. Consultation with a healthcare provider is essential before starting therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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