Product image of Isogelo (Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Sod) supplied by GNH India

Isogelo

Active Ingredient:
Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Sod
Origin:
EU

Isogelo (Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Sod)

Magnesium chloride hexahydrate (together with potassium chloride, sodium chloride, calcium chloride dihydrate and sodium), the active ingredients in Isogelo, is an electrolyte solution presented as a sterile solution for injection for intravenous use. It helps correct electrolyte deficiencies and supports fluid balance in patients requiring replacement therapy.

GNH India supplies Isogelo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

1
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Indications & Clinical Uses

Isogelo is an intravenous electrolyte solution used to restore and maintain normal electrolyte and fluid balance in several clinical situations.

  • Electrolyte deficiency (hypomagnesemia, hypokalemia, hyponatremia, hypocalcemia): replenishes deficient ions and normalises serum concentrations.
  • Fluid replacement: provides isotonic fluid volume to address dehydration or blood loss.
  • Peri‑operative or critical‑care support: maintains electrolyte homeostasis during surgery, trauma or intensive care management.

How It Works

  • Isogelo supplies magnesium, potassium, sodium, calcium and chloride ions directly into the bloodstream. These ions participate in cellular electrical activity, enzyme function and osmotic regulation, thereby restoring normal electrolyte concentrations and supporting fluid distribution across intracellular and extracellular compartments.

Side Effects

Isogelo may be associated with a range of infusion‑related reactions.

Common Side Effects

  • Injection site pain or erythema.
  • Mild hypermagnesemia presenting as flushing or warmth.
  • Transient hyperkalemia causing mild muscle weakness.
  • Slight increase in serum sodium leading to mild thirst.

Serious or Rare Side Effects

  • Severe hypermagnesemia resulting in respiratory depression.
  • Life‑threatening hyperkalemia with cardiac arrhythmia.
  • Anaphylactic or severe hypersensitivity reaction.
  • Fluid overload causing pulmonary edema.
  • Cardiac arrhythmias due to rapid electrolyte shifts.

Precautions & Warnings

Before initiating Isogelo therapy, clinicians should evaluate the patient's electrolyte status and renal function.

  • Assess baseline serum electrolytes: confirm deficiency before infusion.
  • Monitor cardiac rhythm: watch for arrhythmias during rapid correction.
  • Adjust infusion rate in renal impairment: slower rates reduce risk of accumulation.
  • Avoid in known hypermagnesemia, hyperkalemia, or severe hypernatremia.
  • Use caution in patients with heart failure or fluid overload risk.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Isogelo can interact with other agents that affect electrolyte balance or cardiac conduction.

Major Interactions (Avoid)

  • Concurrent administration of additional IV electrolyte solutions: risk of severe electrolyte overload.
  • Digoxin therapy combined with hyperkalemia from Isogelo: may precipitate digoxin toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may potentiate hyperkalemia; monitor potassium levels.
  • Loop diuretics: can cause rapid shifts in calcium and magnesium; adjust dosing.
  • Nephrotoxic antibiotics (e.g., aminoglycosides): monitor renal function and electrolyte trends.

Frequently Asked Questions

Isogelo is an intravenous electrolyte solution indicated for the treatment of electrolyte deficiencies such as hypomagnesemia, hypokalemia, hyponatremia and hypocalcemia, for fluid replacement in dehydration or blood loss, and for supporting electrolyte balance during surgery, trauma or intensive‑care management.

The magnesium chloride, together with potassium, sodium, calcium and chloride ions, is delivered directly into the bloodstream. These ions participate in cellular electrical activity, enzyme cofactors and osmotic regulation, helping to restore normal serum concentrations and maintain fluid equilibrium across body compartments.

The dose of Isogelo is individualized by the prescribing clinician based on the patient’s current electrolyte measurements, clinical condition, renal function and the volume of fluid required. No fixed regimen is provided; the prescriber calculates the appropriate infusion rate and total volume.

The safety of Isogelo in pregnancy or lactation has not been definitively established. Clinicians should weigh the potential benefits against possible risks and consider alternative therapies when possible. Consultation with a maternal‑fetal medicine specialist is recommended.

To order Isogelo, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Isogelo provides a balanced mix of magnesium, potassium, sodium, calcium and chloride, whereas some alternatives such as Ringer's lactate lack magnesium and have different calcium concentrations. The broader ion profile of Isogelo can be advantageous when multiple electrolyte deficits need simultaneous correction.

Isogelo should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the vial in its original packaging until use to maintain sterility and stability.

Isogelo is administered intravenously. The solution is typically infused through a peripheral or central line using a calibrated infusion set. The rate and total volume are determined by the prescriber according to the patient’s electrolyte deficits and fluid needs.

Serious risks include severe hypermagnesemia leading to respiratory depression, life‑threatening hyperkalemia causing cardiac arrhythmia, anaphylactic reactions, and fluid overload that may result in pulmonary edema. Continuous monitoring of electrolytes and cardiac status is essential during infusion.

Isogelo is contraindicated in patients with known hypermagnesemia, hyperkalemia, severe hypernatremia, uncontrolled heart failure, or severe renal impairment where electrolyte clearance is markedly reduced. It should also be avoided in individuals with a documented hypersensitivity to any of its components.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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