Product image of Isolyte (Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Sodium Acetate Trihydrate) supplied by GNH India

Isolyte

Active Ingredient:
Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Sodium Acetate Trihydrate
Origin:
EU

Isolyte (Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Sodium Acetate Trihydrate)

Isolyte, the active ingredient in Isolyte, is an IV electrolyte solution presented as a sterile solution for intravenous use. It provides isotonic fluid and essential electrolytes to restore fluid balance and correct electrolyte disturbances in patients requiring fluid replacement, such as those undergoing surgery, trauma care, or dehydration.

GNH India supplies Isolyte as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and clinics worldwide, ensuring regulatory‑grade quality and reliable logistics. Our distribution network adheres to Good Distribution Practice standards, facilitating timely delivery across multiple regions.

Manufacturer / TM Owner

Fresenius Kabi Hungary Kft.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Isolyte is used to manage fluid and electrolyte disorders by providing isotonic replacement solutions.

  • Fluid replacement: restores intravascular volume and maintains hemodynamic stability.
  • Electrolyte imbalance correction: supplies sodium, potassium, magnesium and acetate to normalize serum electrolyte concentrations.
  • Acid‑base balance maintenance: acetate serves as a buffer to help correct metabolic acidosis.
  • Surgical peri‑operative care: supports patients during anesthesia and postoperative recovery.
  • Trauma resuscitation: provides rapid volume expansion in hemorrhagic shock.

How It Works

  • Isolyte delivers a balanced mixture of sodium chloride, potassium chloride, magnesium chloride hexahydrate and sodium acetate trihydrate in an isotonic carrier. The sodium and chloride ions expand extracellular fluid volume, while potassium and magnesium replenish intracellular stores. Sodium acetate is metabolized to bicarbonate, contributing to systemic buffering and correction of metabolic acidosis. Together, these electrolytes restore osmotic balance, support cellular function and maintain acid‑base homeostasis.

Side Effects

Isolyte may be associated with infusion‑related adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Phlebitis at infusion site: mild inflammation or pain.
  • Hypernatremia: elevated serum sodium if administered excessively.
  • Hyperkalemia: increased serum potassium levels.
  • Hypocalcemia: transient reduction due to magnesium infusion.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe hypersensitivity requiring immediate intervention.
  • Electrolyte overload: severe hypermagnesemia or hyperkalemia leading to cardiac arrhythmia.
  • Metabolic alkalosis: rapid shift causing over‑correction of acidosis.
  • Fluid overload: pulmonary edema in patients with cardiac dysfunction.
  • Seizures: due to severe electrolyte disturbances.

Precautions & Warnings

When using Isolyte, clinicians should observe several precautions to minimize risks and ensure optimal therapy.

  • Assess electrolyte status: check serum sodium, potassium, magnesium and acid‑base balance before infusion.
  • Adjust infusion rate: tailor speed to patient’s cardiac and renal function to avoid overload.
  • Monitor fluid balance: track input/output and weight to detect fluid accumulation.
  • Use compatible IV solutions: avoid mixing with calcium‑containing solutions that may precipitate.
  • Contraindications: do not use in patients with known hypersensitivity to any component.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Isolyte can interact with other medications, influencing electrolyte levels or infusion compatibility.

Major Interactions (Avoid)

  • Calcium gluconate or calcium chloride: may precipitate with magnesium, causing line blockage.
  • Loop diuretics (e.g., furosemide): can exacerbate electrolyte shifts, requiring close monitoring.
  • ACE inhibitors or ARBs: increase risk of hyperkalemia when combined with potassium‑rich solutions.

Moderate Interactions (Monitor Closely)

  • Digoxin: altered potassium levels may affect drug toxicity.
  • Antacids containing aluminum or magnesium: additive magnesium load may lead to hypermagnesemia.
  • Blood transfusions: concurrent infusion may affect electrolyte balance; monitor serum values.

Frequently Asked Questions

Isolyte is an intravenous electrolyte solution used to replace lost body fluids, correct electrolyte disturbances such as low potassium or magnesium, and help maintain acid‑base balance in patients who require rapid fluid resuscitation, peri‑operative support, or treatment of dehydration.

Isolyte supplies a balanced mix of sodium, potassium, magnesium and acetate ions in an isotonic carrier. Sodium and chloride expand extracellular volume, potassium and magnesium replenish intracellular stores, and acetate is metabolized to bicarbonate, providing a buffering effect that assists in correcting metabolic acidosis.

The dose of Isolyte is individualized by the prescribing clinician based on the patient’s current fluid status, electrolyte laboratory values, underlying medical condition, and the desired rate of volume replacement. No fixed regimen is provided; the prescriber sets the appropriate volume and infusion speed.

Safety data for Isolyte in pregnancy and lactation are limited. It should be used only if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made by the treating physician in consultation with obstetric specialists.

To order Isolyte, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling if needed) and any required import documentation.

Isolyte offers a balanced combination of sodium, potassium, magnesium and acetate, making it suitable for both volume expansion and metabolic buffering. Compared with simpler saline solutions, it provides additional electrolytes and a built‑in buffer, reducing the need for separate bicarbonate administration in cases of metabolic acidosis.

Isolyte should be stored at 2‑8 °C in a refrigerator. Keep the container in its original packaging, protect it from light, and avoid freezing or shaking the solution, as these actions could compromise sterility and stability.

Isolyte is administered intravenously through a sterile infusion set. The infusion rate is set by the healthcare professional according to the patient’s clinical needs, and the solution is typically delivered via a peripheral or central venous line under aseptic conditions.

Serious risks include severe electrolyte overload (e.g., hypermagnesemia or hyperkalemia) that can cause cardiac arrhythmias, anaphylactic reactions, and rapid fluid overload leading to pulmonary edema. Continuous monitoring of electrolyte levels and fluid status is essential to mitigate these risks.

Isolyte should be avoided in patients with known hypersensitivity to any of its components, in those with uncontrolled hyperkalemia or hypermagnesemia, and in individuals for whom rapid fluid expansion could exacerbate heart failure or severe renal impairment without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Sodium Acetate Trihydrate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT