Isopeg (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

The polyethylene glycol component draws water into the intestinal lumen by osmosis, while the added electrolytes maintain fluid balance. This increased intraluminal water softens the stool, expands its volume, and stimulates peristalsis, facilitating easier bowel movements without systemic absorption.

The dosage of Isopeg is individualized by the prescribing clinician based on the patient’s condition, age, renal function and response. The prescriber determines the appropriate volume and frequency, and the product should be taken exactly as directed on the prescription label.

Safety data for Isopeg in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional after evaluating the clinical situation.

To order Isopeg, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Isopeg combines polyethylene glycol with electrolytes, offering a balanced osmotic effect that reduces the risk of severe electrolyte shifts compared with plain PEG solutions. Unlike stimulant laxatives, it works by water retention rather than stimulating intestinal muscle, providing a gentler and more predictable cleansing profile.

Isopeg should be stored at ambient temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture and direct sunlight, and store it in its original packaging to maintain product stability throughout its shelf life.

Isopeg is supplied as an oral solution. The prescribed volume is measured using the provided dosing device or a calibrated syringe, then ingested with water. It is usually taken on an empty stomach, but patients should follow the specific instructions given by their healthcare provider.

Serious risks include severe dehydration and significant electrolyte disturbances such as hyponatraemia, hyperkalaemia or hypochloraemia. Patients should be monitored for signs of excessive fluid loss, dizziness, muscle cramps or cardiac irregularities, especially if they have underlying renal or cardiac disease.

Isopeg is contraindicated in individuals with known or suspected mechanical bowel obstruction, intestinal perforation, severe renal impairment, uncontrolled heart failure, or hypersensitivity to any of its components. It should also be used with caution in the elderly and in patients on medications that affect fluid or electrolyte balance.