Product image of Isoprenalina Tillomed (Isoprenaline Hydrochloride) supplied by GNH India

Isoprenalina Tillomed

Active Ingredient:
Isoprenaline Hydrochloride
Origin:
EU

Isoprenalina Tillomed (Isoprenaline Hydrochloride)

Isoprenaline, the active ingredient in Isoprenalina Tillomed, is a beta‑adrenergic agonist presented as a sterile solution for intravenous or subcutaneous use. It is employed to increase heart rate and contractility in bradyarrhythmias and to provide bronchodilation in acute bronchospasm. The formulation complies with EU pharmaceutical standards and is intended for use under medical supervision.

GNH India supplies Isoprenalina Tillomed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Laboratorios Tillomed Spain, S.L.U

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Isoprenaline acts on the beta‑adrenergic system to treat several acute cardiovascular and respiratory conditions.

  • Bradycardia: raises heart rate to maintain adequate cardiac output.
  • Heart block: improves conduction through the atrioventricular node.
  • Cardiac arrest: provides temporary circulatory support during resuscitation.
  • Bronchospasm: relaxes airway smooth muscle to relieve acute bronchoconstriction.

How It Works

  • Isoprenaline is a non‑selective β‑adrenergic receptor agonist that binds to both β1 and β2 receptors. Stimulation of β1 receptors in the heart increases cyclic AMP, leading to enhanced calcium influx, faster depolarization, and stronger myocardial contraction. Activation of β2 receptors in bronchial smooth muscle causes relaxation through a similar cAMP‑mediated pathway, resulting in bronchodilation.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Tachycardia: rapid increase in heart rate.
  • Tremor: fine shaking of hands or limbs.
  • Headache: mild to moderate cranial pain.
  • Nausea: feeling of stomach discomfort.

Serious or Rare Side Effects

  • Arrhythmias: potentially life‑threatening irregular heart rhythms.
  • Myocardial ischemia: reduced blood flow to heart muscle.
  • Severe hypotension: marked drop in blood pressure.

Precautions & Warnings

Careful assessment and monitoring are required before and during therapy.

  • Cardiac monitoring: continuous ECG and blood pressure observation.
  • Dose titration: start low and adjust based on clinical response.
  • Contraindications: avoid in patients with pheochromocytoma or uncontrolled hypertension.
  • Caution in ischemic heart disease: risk of worsening myocardial oxygen demand.
  • Pregnancy and lactation: safety not established; use only if benefit outweighs risk.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Isoprenaline may interact with several drug classes, altering its efficacy or safety.

Major Interactions (Avoid)

  • Beta‑blockers: antagonize therapeutic effects and may precipitate severe bradycardia.
  • MAO inhibitors: can potentiate hypertensive responses.
  • Tricyclic antidepressants: increase risk of arrhythmias.

Moderate Interactions (Monitor Closely)

  • Calcium channel blockers: may enhance cardiac stimulation.
  • Digoxin: combined use can predispose to ventricular ectopy.

Frequently Asked Questions

Isoprenalina Tillomed is indicated for the acute management of bradycardia, heart block, cardiac arrest, and severe bronchospasm. It works by stimulating beta‑adrenergic receptors to increase heart rate, improve cardiac contractility, and relax airway smooth muscle, providing rapid physiological support in emergency settings.

Isoprenaline is a non‑selective β‑adrenergic agonist. By binding to β1 receptors in the heart, it raises cyclic AMP levels, leading to faster depolarization and stronger contractions. Activation of β2 receptors in the lungs causes smooth‑muscle relaxation, producing bronchodilation. These combined actions support circulation and breathing during acute events.

The specific dose of Isoprenalina Tillomed is determined by the prescribing clinician based on the patient’s condition, weight, and response. Dosing regimens are individualized and adjusted according to continuous cardiac and respiratory monitoring to achieve the desired therapeutic effect while minimizing adverse reactions.

Safety data for isoprenaline in pregnancy and lactation are limited. The drug should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Clinicians must evaluate each case carefully and discuss uncertainties with the patient.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifying trade or institutional credentials before providing pricing, availability, shipping details (including cold‑chain if needed), and necessary import documentation.

Isoprenaline is a non‑selective β‑agonist, affecting both β1 and β2 receptors, whereas many alternatives such as albuterol are selective for β2 receptors. This broader activity makes isoprenaline useful for cardiac stimulation as well as bronchodilation, but it also carries a higher risk of cardiac side effects compared with β2‑selective agents.

Isoprenalina Tillomed must be stored at 2‑8 °C in a refrigerator. Keep the vial in its original packaging, protect it from light, and avoid freezing or shaking. Do not use the product if it appears discolored or if the seal is broken.

The drug is supplied as a sterile solution for intravenous or subcutaneous injection. Administration is performed by qualified healthcare professionals under continuous monitoring, with the dose titrated to achieve the desired heart rate or bronchodilation while observing for adverse reactions.

Serious risks include life‑threatening arrhythmias, myocardial ischemia, severe hypotension, and allergic reactions such as anaphylaxis. Prompt recognition and immediate medical intervention are essential if any of these events occur during therapy.

Patients with known hypersensitivity to isoprenaline, pheochromocytoma, uncontrolled hypertension, or severe coronary artery disease should not receive the drug. Additionally, concurrent use of beta‑blockers or other agents that antagonize beta‑adrenergic activity is contraindicated.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.