Isoprenaline Macure (Isoprenaline Hydrochloride)

Isoprenaline Hydrochloride acts as a non‑selective β‑adrenergic agonist. It binds to β1 receptors in the heart, raising cyclic AMP levels and enhancing cardiac contractility and rate. Simultaneously, activation of β2 receptors in the lungs relaxes bronchial smooth muscle, producing bronchodilation.

The dose of Isoprenaline Macure is individualized and must be determined by a qualified prescriber based on the patient’s clinical condition, response, and tolerance. Healthcare professionals adjust the infusion rate to achieve the desired therapeutic effect while monitoring vital signs.

Safety data for Isoprenaline during pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To order Isoprenaline Macure, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and necessary import documentation.

Isoprenaline is a non‑selective β‑agonist, providing both cardiac stimulation (β1) and bronchodilation (β2). Compared with selective β2 agents such as albuterol, Isoprenaline has a stronger cardiac effect, making it suitable for bradyarrhythmias but requiring careful cardiovascular monitoring.

Isoprenaline Macure should be stored at 2‑8 °C in a refrigerator, protected from light, and must not be frozen or shaken. Keep the vial in its original packaging until use and discard any solution that appears discolored or particulate.

Isoprenaline is administered intravenously, typically as a continuous infusion or intermittent bolus under cardiac monitoring. The infusion rate is titrated to achieve the desired increase in heart rate or bronchodilation, and the drug must be diluted according to the manufacturer’s instructions before administration.

The most serious risks include severe arrhythmias such as ventricular tachycardia, myocardial ischemia due to increased oxygen demand, pulmonary edema from excessive vasodilation, and profound hypotension. Immediate medical attention is required if any of these events occur.

Isoprenaline is contraindicated in patients with known hypersensitivity to the drug, uncontrolled tachyarrhythmias, severe coronary artery disease, acute myocardial infarction, and in those receiving non‑selective β‑blockers without appropriate adjustment. Caution is also advised in patients with hyperthyroidism or pheochromocytoma.