Isoptin Retard (Verapamil Hydrochloride)

Verapamil Hydrochloride blocks L‑type calcium channels in cardiac and vascular smooth muscle. By limiting calcium entry, it reduces the force of heart muscle contraction, slows conduction through the atrioventricular node, and causes arterial vasodilation, which together lower blood pressure and relieve angina.

The specific dose of Isoptin Retard is determined by the prescribing clinician based on the patient’s medical condition, response to therapy, and other individual factors. Dosage adjustments may be needed for renal or hepatic impairment, and the medication is typically taken once daily with food.

Safety data for Verapamil Hydrochloride in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any possible risk to the fetus or infant. Healthcare providers will assess each case individually and discuss alternatives when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Isoptin Retard (verapamil) is a non‑dihydropyridine calcium channel blocker, distinguished by its pronounced effect on cardiac conduction and contractility. In contrast, dihydropyridine agents such as amlodipine primarily cause peripheral vasodilation with less impact on heart rate, making verapamil preferable for certain arrhythmias.

Isoptin Retard tablets should be stored at room temperature, below 25 °C, in the original container to protect them from moisture and light. Keep the medication out of reach of children and do not use after the expiry date printed on the package.

Isoptin Retard is taken orally as an extended‑release tablet, usually once daily. It should be swallowed whole with a glass of water and can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort.

Serious risks include marked slowing of the heart rate (bradycardia), severe low blood pressure (hypotension), and heart block, which can be life‑threatening. Patients should be monitored for these events, especially when initiating therapy or when combined with other AV‑node‑acting drugs.

Isoptin Retard is contraindicated in patients with known hypersensitivity to verapamil, severe left ventricular dysfunction, second‑ or third‑degree atrioventricular block without a pacemaker, and in those with cardiogenic shock. It should also be avoided in patients taking certain interacting medications without careful supervision.