Isoptin Sr (Verapamil Hydrochloride)

Verapamil hydrochloride blocks L-type calcium channels in cardiac and vascular smooth muscle. By reducing calcium entry into cells, it decreases the force of heart muscle contraction, slows conduction through the atrioventricular node, and relaxes blood vessels, which together lower blood pressure and stabilize abnormal heart rhythms.

The dose of Isoptin Sr is individualized by the prescribing clinician based on the specific condition being treated, the patient’s age, kidney and liver function, and response to therapy. Dosage adjustments may be required over time, and patients should follow the prescriber’s instructions without self‑adjusting the amount.

Safety data for verapamil during pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss risks and alternatives with their healthcare provider.

To order Isoptin Sr, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Isoptin Sr (verapamil) primarily affects cardiac conduction and contractility, making it useful for arrhythmias and angina. Other calcium channel blockers like amlodipine are more vascular selective, focusing on blood pressure control with fewer cardiac effects. Diltiazem shares some cardiac properties with verapamil but differs in potency and interaction profile, so choice depends on the clinical indication.

Isoptin Sr should be stored at ambient temperature, preferably below 25 °C (77 °F). Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure the packaging remains tightly closed until use.

Isoptin Sr is taken orally, usually as a whole tablet swallowed with a glass of water. It can be taken with or without food, but patients should follow the prescriber’s guidance on timing relative to meals to maintain consistent absorption.

Serious risks include severe bradycardia (slow heart rate), heart block, marked hypotension (low blood pressure), and myocardial depression. Patients should seek immediate medical attention if they experience fainting, dizziness, chest pain, or an irregular heartbeat, as these may signal a potentially life‑threatening reaction.

Isoptin Sr is contraindicated in patients with severe sinus node dysfunction, second‑ or third‑degree atrioventricular block without a pacemaker, uncontrolled heart failure, and those with known hypersensitivity to verapamil or any excipients in the tablet. Clinicians should also exercise caution in individuals with significant hepatic impairment.