Isoptin Sr (Verapamil Hydrochloride)

Verapamil blocks L‑type calcium channels on cardiac and vascular smooth‑muscle cells. By limiting calcium entry, it reduces myocardial contractility, slows conduction through the atrioventricular node, and causes arterial vasodilation. These actions collectively lower blood pressure, decrease myocardial oxygen demand, and help correct irregular heartbeats.

The appropriate dose of Isoptin Sr is determined individually by a qualified prescriber based on the patient’s medical condition, response to therapy, and any concomitant medications. Healthcare professionals adjust the regimen to achieve optimal blood‑pressure control, angina relief, or arrhythmia management while monitoring safety.

Safety data for verapamil in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Physicians should discuss individual circumstances and consider alternative therapies if appropriate.

To place an order, visit the product page on gnhindia.com, enter the required quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Isoptin Sr (verapamil) is a non‑dihydropyridine calcium channel blocker, distinguished by its pronounced effects on cardiac conduction and contractility. Compared with dihydropyridine agents such as amlodipine, verapamil has greater anti‑arrhythmic activity but may cause more bradycardia and AV‑block, making it preferable for certain rhythm disorders while requiring careful monitoring.

Isoptin Sr should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture, excessive heat, and direct sunlight. Do not refrigerate or freeze unless specifically instructed by the manufacturer.

Isoptin Sr is taken orally, usually with a full glass of water. The tablet should be swallowed whole and not chewed or crushed unless directed by a healthcare professional. Dosing times (e.g., with or without food) are determined by the prescriber based on therapeutic goals and tolerability.

Serious risks include marked bradycardia, heart block, severe hypotension, and worsening heart failure. Patients should be monitored for signs of slowed heart rate, fainting, sudden drops in blood pressure, or increased shortness of breath, and any concerning symptoms should be reported to a healthcare provider promptly.

Isoptin Sr is contraindicated in patients with known hypersensitivity to verapamil or any component of the formulation, those with severe hypotension, uncorrected second‑ or third‑degree AV block, sick sinus syndrome without a pacemaker, and in individuals with acute myocardial infarction where its use may worsen outcomes.