Isosorbide Mononitrate Kent Xl Tablets (Isosorbide 5 Mononitrate)

The drug releases nitric oxide after oral absorption. Nitric oxide activates guanylate cyclase, raising cyclic GMP levels in vascular smooth muscle. This leads to vasodilation, lowering preload and afterload, which reduces myocardial oxygen demand and improves coronary perfusion.

The specific dose and dosing schedule are determined by the prescribing healthcare professional based on the patient’s condition, response, and tolerance. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for isosorbide mononitrate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

Enquiries can be submitted via the product page on gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Isosorbide mononitrate is a long‑acting nitrate that provides sustained nitric‑oxide release, whereas other classes such as beta‑blockers or calcium‑channel blockers lower heart rate or contractility. Nitrates are particularly effective for relieving angina triggered by exertion, but they may cause tolerance if not dosed appropriately.

Store the tablets at ambient temperature below 25 °C, in the original container, protected from moisture and light. Keep them out of reach of children and do not use if the packaging is damaged.

The tablets are intended for oral administration. They should be swallowed whole with a glass of water, preferably at the same times each day to maintain steady blood levels. Patients should not crush, chew, or split the tablets unless directed by a healthcare professional.

Serious risks include severe hypotension, syncope, worsening angina, myocardial infarction, and rare allergic reactions such as anaphylaxis. Patients experiencing fainting, chest pain, or signs of an allergic response should seek immediate medical attention.

Individuals with known hypersensitivity to isosorbide mononitrate or any nitrate, those taking phosphodiesterase‑5 inhibitors, or patients with severe hypotension should avoid this medication. It is also contraindicated in patients with certain cardiovascular conditions where vasodilation could be harmful, as determined by a physician.