Itami (Diclofenac Sodium)

Diclofenac sodium works by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for prostaglandin synthesis. By lowering prostaglandin levels in the treated tissue, it reduces inflammation, pain, and swelling at the site of application, offering targeted relief without significant systemic exposure.

The specific dose and frequency of Itami are determined by the prescribing healthcare professional based on the severity of the condition, the size of the treatment area, and patient factors. Patients should follow the prescriber’s instructions and the product label for proper application.

Safety data for topical diclofenac during pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks with their healthcare provider before using Itami. The prescriber will weigh the benefits against any possible risks to mother and child.

To order Itami, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials, then respond with pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Itami contains diclofenac sodium, a well‑studied NSAID with strong COX inhibition, offering effective pain relief and anti‑inflammatory action. Compared with other topical NSAIDs such as ibuprofen or ketoprofen, diclofenac generally provides a higher potency per gram of product, making it a preferred choice for moderate musculoskeletal conditions.

Itami should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight, and extreme heat. Ensure the container is tightly closed when not in use to maintain product stability.

Itami is applied topically to clean, dry, intact skin over the affected area. The prescribed amount is gently massaged until fully absorbed, usually 2–4 times daily, or as directed by the prescriber. Avoid covering the treated area with occlusive dressings unless instructed.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, systemic NSAID effects like gastrointestinal bleeding or ulceration, renal impairment, and hepatotoxicity. Patients should seek immediate medical attention if they experience swelling of the face, difficulty breathing, severe skin reactions, or signs of internal bleeding.

Itami should not be used by individuals with known hypersensitivity to diclofenac, other NSAIDs, or any component of the formulation. It is also contraindicated in patients with active gastrointestinal ulcers, severe heart failure, or uncontrolled hypertension without medical supervision. Pregnant or breastfeeding women should consult a healthcare professional before use.