Itami (Diclofenac Sodium)

Diclofenac sodium inhibits the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for prostaglandin production. By lowering prostaglandin levels, the drug reduces the inflammatory response, leading to decreased pain, swelling and redness at the site where the gel is applied.

The specific amount of Itami to apply and the frequency of use are determined by the prescribing healthcare professional based on the severity of symptoms, the size of the treatment area and individual patient factors. Patients should follow the prescriber’s instructions and the product label.

Safety of topical diclofenac during pregnancy or lactation has not been fully established. Healthcare providers usually recommend avoiding NSAID use unless the potential benefit outweighs the risk. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternative options with their clinician.

To request Itami, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Itami contains diclofenac sodium, a widely studied NSAID with strong anti‑inflammatory and analgesic properties. Compared with other topical NSAIDs such as ibuprofen or ketoprofen gels, diclofenac generally offers a higher potency for musculoskeletal pain and is supported by extensive clinical data for conditions like osteoarthritis.

Itami should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight and sources of heat. Do not freeze the gel, and ensure the container is tightly closed when not in use.

Itami is applied topically to clean, dry skin over the affected area. A thin layer is gently massaged in until fully absorbed, typically 2‑4 times daily or as directed by a healthcare professional. Hands should be washed after application, and the treated skin should not be covered with occlusive dressings unless advised.

Serious risks, though rare, include severe allergic reactions such as rash, swelling, or difficulty breathing, and systemic NSAID effects like gastrointestinal bleeding, liver enzyme elevation, or renal impairment. Patients should stop use and seek medical attention if they experience any signs of a serious reaction.

Itami should be avoided by individuals with known hypersensitivity to diclofenac, other NSAIDs, or any component of the formulation. It is also contraindicated on broken, infected or inflamed skin, and in patients with a history of severe cardiovascular, gastrointestinal or renal disease unless specifically approved by a physician.