Itami (Diclofenac Sodium)

Diclofenac sodium works by reversibly inhibiting the cyclooxygenase (COX‑1 and COX‑2) enzymes that catalyze prostaglandin production. Lower prostaglandin levels diminish inflammation, pain signaling, and fever responses. When applied topically, the drug concentrates at the site of injury, offering targeted relief while limiting systemic exposure.

The appropriate amount of Itami to apply is determined by the prescribing healthcare professional based on the severity of the condition, the size of the treatment area, and individual patient factors. Patients should follow the specific instructions provided on the label or by their clinician and not exceed the recommended amount.

Safety of topical diclofenac during pregnancy or lactation has not been definitively established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss the potential risks and benefits with their healthcare provider before using Itami, as alternative treatments may be preferred.

To order Itami, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Itami contains diclofenac sodium, a well‑studied NSAID with strong COX inhibition, offering potent anti‑inflammatory and analgesic effects. Compared with other topical NSAIDs such as ibuprofen or ketoprofen gels, diclofenac generally provides longer‑lasting pain relief and is frequently chosen for osteoarthritis and sports‑related injuries. Individual response may vary, so clinicians select the product best suited to the patient’s condition.

Itami should be stored below 25 °C in its original packaging, protected from moisture, heat and direct sunlight. Keep the container tightly closed when not in use. Do not freeze the product, and keep it out of reach of children.

Clean and dry the skin area before use. Apply a thin layer of Itami to the affected site and gently massage until it is absorbed. Wash your hands after application unless the hands are the treatment area. Do not cover the treated area with occlusive dressings unless directed by a healthcare professional.

Serious risks, although rare, include severe allergic reactions such as dermatitis, Stevens‑Johnson syndrome, systemic NSAID effects like gastrointestinal bleeding, liver enzyme abnormalities, and kidney function impairment. If any signs of severe rash, swelling, abdominal pain, dark urine, or unexplained fatigue occur, discontinue use and seek medical attention promptly.

Itami should be avoided by individuals with known hypersensitivity to diclofenac, other NSAIDs, or any component of the formulation. It is also contraindicated on broken, infected or inflamed skin, in children under 12 years without medical advice, and in patients with a history of severe cardiovascular, gastrointestinal or renal disease unless specifically approved by a physician.