Product image of Itamifast (Diclofenac Potassium) supplied by GNH India

Itamifast

Active Ingredient:
Diclofenac Potassium
Origin:
EU

Itamifast (Diclofenac Potassium)

Diclofenac potassium, the active ingredient in Itamifast, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for systemic use. It treats mild to moderate pain and inflammatory musculoskeletal conditions such as osteoarthritis, rheumatoid arthritis, and dysmenorrhea, providing short‑term relief for adults.
GNH India supplies Itamifast as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Fidia Farmaceutici S.P.A

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Indications & Clinical Uses

Diclofenac potassium is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

  • Mild to moderate pain: provides analgesic relief for acute pain episodes.
  • Osteoarthritis: helps reduce joint pain and improve mobility.
  • Rheumatoid arthritis: alleviates inflammatory joint pain and swelling.
  • Dysmenorrhea: relieves menstrual cramps and associated discomfort.

How It Works

  • Diclofenac potassium reversibly inhibits both COX‑1 and COX‑2 enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis leads to diminished inflammation, pain signaling, and fever responses, accounting for its analgesic and anti‑inflammatory effects throughout the body.

Side Effects

Adverse reactions may range from mild to severe, depending on individual susceptibility and duration of therapy.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache or dizziness.
  • Skin rash or mild itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Elevated liver enzymes or hepatic injury.
  • Renal impairment or acute kidney injury.
  • Severe skin reactions such as Stevens‑Johnson syndrome.
  • Anaphylactic or hypersensitivity reactions.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess gastrointestinal risk: avoid use in patients with active ulcer disease or a history of GI bleeding.
  • Monitor renal function: adjust or discontinue in patients with significant renal impairment.
  • Check for hypersensitivity: contraindicated in individuals allergic to diclofenac or other NSAIDs.
  • Use caution in cardiovascular disease: evaluate thrombotic risk, especially in patients with prior events.
  • Limit alcohol consumption: concurrent use may increase GI bleeding risk.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Diclofenac potassium can interact with several drug classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Lithium: diclofenac may raise lithium serum concentrations, risking toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or diuretics: may reduce renal function; monitor creatinine.
  • Corticosteroids: combined use raises the chance of gastric ulceration.

Frequently Asked Questions

Itamifast contains diclofenac potassium, an NSAID indicated for the short‑term relief of mild to moderate pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and dysmenorrhea. It may also be prescribed for other acute musculoskeletal pain where inflammation is a primary component.

Diclofenac potassium works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 (COX‑1 and COX‑2) enzymes. This inhibition reduces the synthesis of prostaglandins, which are mediators of inflammation, pain, and fever, thereby providing analgesic and anti‑inflammatory effects throughout the body.

The appropriate dose of Itamifast is determined by the prescribing healthcare professional based on the individual’s medical condition, severity of symptoms, and overall health status. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

Safety of diclofenac potassium in pregnancy or lactation has not been definitively established. It is generally advised to avoid NSAIDs, including diclofenac, during the third trimester of pregnancy and to discuss potential risks with a healthcare provider before using it while pregnant or breastfeeding.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Itamifast (diclofenac potassium) is a fast‑acting NSAID that often provides quicker pain relief compared with some other oral NSAIDs such as ibuprofen. Its potassium salt form may be absorbed more rapidly, but the overall safety profile, including gastrointestinal and cardiovascular risks, remains similar to other NSAIDs.

Itamifast should be stored at ambient temperature below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Itamifast is taken orally, usually with a full glass of water. It may be taken with or without food, although taking it with food can help reduce gastrointestinal discomfort. The exact timing and frequency should follow the prescriber’s directions.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe skin reactions such as Stevens‑Johnson syndrome, hepatic injury, renal impairment, and increased cardiovascular events. Patients should seek immediate medical attention if they experience symptoms like black stools, severe abdominal pain, rash, or unexplained swelling.

Itamifast should be avoided in individuals with known hypersensitivity to diclofenac, other NSAIDs, or any component of the formulation. It is also contraindicated in patients with active gastrointestinal ulceration, severe heart failure, or those who have had a recent coronary artery bypass graft surgery.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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