Product image of Itomed (Itopride Hydrochloride) supplied by GNH India

Itomed

Active Ingredient:
Itopride Hydrochloride
Origin:
EU

Itomed (Itopride Hydrochloride)

Itopride Hydrochloride, the active ingredient in Itomed, is a prokinetic presented as an oral tablet for oral use. It enhances gastrointestinal motility and is used to relieve symptoms of functional dyspepsia, gastroesophageal reflux disease, and post‑prandial fullness in adult patients.

GNH India supplies Itomed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and providing reliable global distribution.

Manufacturer / TM Owner

Pro.Med.Cs Praha A.S.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Itopride Hydrochloride is a prokinetic agent that improves upper‑gastrointestinal motility and is indicated for several functional digestive disorders.

  • Functional dyspepsia: reduces epigastric pain, early satiety and post‑prandial fullness.
  • Gastroesophageal reflux disease (GERD): alleviates reflux symptoms by promoting gastric emptying.
  • Postprandial fullness: diminishes the sensation of excessive fullness after meals.

How It Works

  • Itopride Hydrochloride acts by antagonizing dopamine D2 receptors in the gastrointestinal tract and inhibiting acetylcholinesterase, which leads to increased acetylcholine release. The rise in acetylcholine enhances smooth‑muscle contractility, thereby accelerating gastric emptying and improving overall gastrointestinal motility.

Side Effects

Adverse reactions to Itomed are generally mild, but serious events can occur.

Common Side Effects

  • Nausea
  • Dry mouth
  • Abdominal discomfort
  • Headache
  • Dizziness
  • Diarrhea

Serious or Rare Side Effects

  • Extrapyramidal symptoms (e.g., dystonia, tremor)
  • Severe allergic reactions, including anaphylaxis
  • Cardiac arrhythmias
  • Hepatic dysfunction
  • Neutropenia

Precautions & Warnings

Before prescribing Itomed, clinicians should consider several safety aspects.

  • Assess renal and hepatic function: evaluate baseline organ status.
  • Use with caution in elderly patients: monitor for increased sensitivity.
  • Avoid in patients with known hypersensitivity to itopride or excipients.
  • Monitor for extrapyramidal symptoms during therapy.
  • Store at room temperature: keep in the original packaging, protect from moisture.

Avoid Interactions

Itomed may interact with other medicines; some combinations require avoidance while others need close monitoring.

Major Interactions (Avoid)

  • Concomitant use with strong anticholinergic agents may diminish prokinetic effect.
  • Co‑administration with other dopamine antagonists can increase risk of extrapyramidal reactions.

Moderate Interactions (Monitor Closely)

  • Antacids may reduce absorption; separate dosing by at least 2 hours.
  • CYP3A4 substrates could have altered plasma levels; monitor therapeutic response.
  • Non‑steroidal anti‑inflammatory drugs may increase gastrointestinal irritation; observe for symptoms.

Frequently Asked Questions

Itomed contains itopride hydrochloride, a prokinetic medication indicated for functional dyspepsia, gastroesophageal reflux disease (GERD), and post‑prandial fullness. In these conditions it helps improve gastric emptying and reduces upper‑abdominal discomfort, providing symptomatic relief for adult patients.

Itopride works by blocking dopamine D2 receptors in the gastrointestinal tract and inhibiting the enzyme acetylcholinesterase. This dual action raises acetylcholine levels, which stimulates smooth‑muscle contraction and accelerates gastric emptying, thereby normalising motility and alleviating related symptoms.

The dosage of Itomed is determined by the prescribing healthcare professional based on the individual’s condition, age, and response to therapy. Prescribers follow local guidelines and may adjust the regimen as needed; patients should follow the specific instructions provided by their doctor.

Safety data for itopride during pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any possible risk to the fetus or infant. Healthcare providers will evaluate the risk‑benefit profile before prescribing it to pregnant or nursing women.

To request Itomed, visit the product page on gnhindia.com, enter the desired quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Itopride differs from agents such as metoclopramide by having a dual mechanism—dopamine antagonism and acetylcholinesterase inhibition—while generally presenting a lower risk of central nervous system side effects. It is often preferred when patients experience intolerable extrapyramidal symptoms with other dopamine antagonists.

Itomed should be stored at room temperature, preferably below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiry date indicated on the label.

Itomed is taken orally, usually with a glass of water. It can be administered with or without food, but if an antacid is prescribed, it should be taken at least two hours apart to avoid reduced absorption. Patients should follow the dosing schedule advised by their prescriber.

While most adverse events are mild, serious risks include extrapyramidal reactions such as dystonia or tremor, severe allergic responses including anaphylaxis, cardiac arrhythmias, hepatic dysfunction, and neutropenia. Any of these symptoms require immediate medical attention.

Itomed is contraindicated in individuals with known hypersensitivity to itopride hydrochloride or any of its excipients. Caution is also advised for patients with severe hepatic or renal impairment, and it should be avoided in those taking other dopamine antagonists that could increase the risk of movement disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.