Itraconazol Actavis (Itraconazole)

Itraconazole blocks the fungal enzyme lanosterol 14α‑demethylase, which is needed to produce ergosterol, a key component of the fungal cell membrane. Without ergosterol, the membrane becomes defective, inhibiting fungal growth and leading to cell death.

The appropriate dose of Itraconazol Actavis is determined by the prescribing healthcare professional based on the specific infection, patient weight, renal and hepatic function, and other clinical factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for itraconazole in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with fluconazole, another azole, itraconazole has a broader spectrum against molds such as Aspergillus and offers better activity for certain dermatophytes. However, itraconazole is more prone to drug‑drug interactions and may have a higher risk of hepatotoxicity, requiring careful monitoring.

Store Itraconazol Actavis at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and discard any product that appears discoloured or damaged.

Itraconazol Actavis is taken orally, usually with food to enhance absorption. The tablets or capsules should be swallowed whole with a full glass of water and not chewed or crushed unless specifically instructed by a healthcare professional.

Serious risks include liver injury ranging from elevated enzymes to hepatitis, worsening of congestive heart failure, and severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome. Patients should be monitored for signs of these conditions and seek immediate medical attention if they occur.

Itraconazol Actavis should be avoided in individuals with known hypersensitivity to itraconazole or other azole antifungals, in patients with severe liver disease, and in those with existing congestive heart failure unless the benefits clearly outweigh the risks.