Itraconazolo Eg (Itraconazole)

Itraconazole blocks the fungal enzyme lanosterol 14α‑demethylase, a key step in ergosterol synthesis. Ergosterol is essential for fungal cell membrane integrity; its depletion disrupts membrane formation, leading to impaired growth and eventual death of the fungal cells.

The specific dose of Itraconazolo Eg is determined by the prescribing clinician based on the type and severity of the infection, patient weight, liver function and other individual factors. Only a qualified healthcare professional should set the dosing regimen.

Itraconazolo Eg is classified as Pregnancy Category D, indicating evidence of fetal risk, and it should not be used during pregnancy unless the potential benefit justifies the risk. It is also excreted in breast milk, so breastfeeding is not recommended while on therapy.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Compared with other azole antifungals, itraconazole offers a broad spectrum covering many systemic mycoses and has good activity against dermatophytes. It is often preferred when fluconazole is less effective, but it has a higher potential for drug‑drug interactions and liver toxicity, requiring careful monitoring.

Itraconazolo Eg should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and light. Keeping the product in a dry, cool place helps maintain its stability and potency.

Itraconazolo Eg is taken orally, usually with a full glass of water. The tablet or capsule should be swallowed whole and not chewed or crushed, unless the prescribing information specifies otherwise. Food may affect absorption, so follow the prescriber’s instructions regarding meals.

The most serious risks include hepatotoxicity, which can manifest as elevated liver enzymes or severe liver injury, and rare but severe skin reactions such as Stevens‑Johnson syndrome. Cardiac failure may worsen in susceptible patients, and rare visual disturbances have been reported. Prompt medical attention is required if any of these occur.

Itraconazolo Eg is contraindicated in patients with known hypersensitivity to itraconazole or any azole antifungal, in those with severe liver disease, and in pregnant women unless absolutely necessary. Individuals with congestive heart failure should use it only under strict medical supervision.