Itraisdin (Itraconazole)

Itraconazole blocks the fungal enzyme lanosterol 14α‑demethylase, a key step in ergosterol synthesis. Without ergosterol, the fungal cell membrane becomes unstable, leading to impaired growth and eventual death of the fungus.

The dosage of Itraisdin is determined by the prescribing clinician based on the specific infection, severity, patient weight, renal and hepatic function, and other individual factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for itraconazole in pregnancy and lactation are limited. It should be avoided unless the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To request Itraisdin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with older azoles such as fluconazole, itraconazole has a broader spectrum covering many dermatophytes and dimorphic fungi. It is often chosen when infections are resistant to first‑line agents or when a wider range of fungi must be covered, though it may have more drug‑interaction potential.

Itraisdin should be stored at ambient temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Itraisdin is taken orally, usually with food or a full glass of water to improve absorption. The exact administration schedule—such as once or twice daily—depends on the prescriber’s recommendation and the specific infection being treated.

The most serious risks include liver toxicity, which may present as elevated liver enzymes or hepatitis, and severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome. Cardiac effects like QT prolongation can also occur, especially when combined with other QT‑prolonging drugs.

Patients with known hypersensitivity to itraconazole or any azole antifungal should avoid Itraisdin. Those with severe liver disease, uncontrolled heart rhythm disorders, or who are taking contraindicated medications (e.g., strong CYP3A4 inducers) should not use it without medical supervision.