Product image of Ivabradin Aristo (Ivabradine) supplied by GNH India

Ivabradin Aristo

Active Ingredient:
Ivabradine
Origin:
EU

Ivabradin Aristo (Ivabradine)

Ivabradine, the active ingredient in Ivabradin Aristo, is a If channel inhibitor presented as an oral tablet for oral use. It lowers heart rate and is employed in the management of chronic stable angina and certain forms of heart failure.

GNH India supplies Ivabradin Aristo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aristo Pharma Gmbh (Art 57)

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Indications & Clinical Uses

  • Ivabradin Aristo acts on the cardiac If current to control heart rate in specific cardiovascular conditions.
  • Chronic stable angina: reduces the frequency of angina attacks by lowering heart rate in patients with documented coronary artery disease.
  • Heart failure: improves symptoms and may decrease hospitalisations in patients with reduced ejection fraction by maintaining a controlled heart rate.

How It Works

  • Ivabradine selectively inhibits the funny (If) current in the sinoatrial node, which is responsible for spontaneous depolarisation. By blocking this inward sodium/potassium mixed current, the drug slows the pacemaker activity, leading to a dose‑dependent reduction in heart rate without affecting myocardial contractility or blood pressure.

Side Effects

Ivabradin Aristo may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Visual disturbances (phosphenes or luminous phenomena)
  • Bradycardia (slow heart rate)
  • Headache
  • Dizziness
  • Fatigue
  • Nausea

Serious or Rare Side Effects

  • Symptomatic atrial fibrillation
  • Severe bradycardia requiring medical intervention
  • Hypotension with syncope
  • Persistent visual impairment
  • Heart block of any degree
  • Allergic reactions such as rash or angioedema

Precautions & Warnings

  • Before prescribing Ivabradin Aristo, clinicians should evaluate cardiovascular status and concomitant medications.
  • Assess baseline heart rate: ensure resting rate is ≥70

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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