Product image of Ivabradina Pharmakern (Ivabradine Hydrochloride) supplied by GNH India

Ivabradina Pharmakern

Active Ingredient:
Ivabradine Hydrochloride
Origin:
EU

Ivabradina Pharmakern (Ivabradine Hydrochloride)

Ivabradine, the active ingredient in Ivabradina Pharmakern, is a selective sinus node If channel inhibitor presented as an oral formulation for oral use. It lowers heart rate without affecting myocardial contractility or blood pressure and is employed in the management of chronic stable angina and heart failure with reduced ejection fraction.

GNH India supplies Ivabradina Pharmakern as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide to meet diverse therapeutic needs, with reliable logistics and regulatory support.

Manufacturer / TM Owner

Pharmakern Portugal – Produtos Farmacêuticos, Sociedade Unipessoal, Lda.

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Indications & Clinical Uses

  • Ivabradine is used to manage conditions where reduction of heart rate improves clinical outcomes.
  • Chronic stable angina pectoris: reduces frequency of angina attacks and improves exercise tolerance.
  • Heart failure with reduced ejection fraction (in combination with beta‑blockers): lowers heart rate and may improve symptoms and functional capacity.
  • Elevated resting heart rate in patients on optimal therapy: helps achieve target heart rate when other agents are insufficient.

How It Works

  • Ivabradine selectively blocks the funny (If) current in the sino‑atrial node by binding to the intracellular side of the HCN channel. This inhibition slows the spontaneous depolarization of pacemaker cells, resulting in a reduction of heart rate without altering myocardial contractility, ventricular repolarisation, or systemic blood pressure, and does not affect AV‑node conduction or coronary blood flow, making

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GNH India Pharmaceuticals Limited

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