Product image of Биксебра (Ivabradine) supplied by GNH India

Биксебра

Active Ingredient:
Ivabradine
Origin:
EU

Биксебра (Ivabradine)

Биксебра (Ivabradine) is a prescription medication used to lower heart rate in adults with chronic stable angina or heart failure. It works by slowing the heart’s natural pacemaker activity. This EU-made oral tablet is taken twice daily as directed by a healthcare provider. Always follow usage instructions for best results.

Manufacturer / TM Owner

Krka, D.D., Novo Mesto

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Indications & Clinical Uses

  • Ivabradine is primarily used to reduce heart rate in adults with chronic stable angina pectoris, a condition marked by chest pain due to reduced blood flow to the heart. It is also prescribed for patients with heart failure with reduced ejection fraction to improve symptoms and reduce hospitalization risk. This medication helps the heart beat more efficiently by modulating the sinoatrial node’s activity. It is not intended for emergency use or in patients with unstable angina.

Side Effects

  • After taking Ivabradine, many users notice a gradual reduction in their resting heart rate, which can help alleviate symptoms like chest discomfort and shortness of breath during physical activity. Some people may experience temporary visual effects, such as brightness or halos around lights, especially when moving between light and dark environments. These effects are usually mild and tend to diminish over time. It may take several weeks of consistent use to observe the full benefits.

Precautions & Warnings

  • Ivabradine should be stored in a cool, dry place away from direct sunlight and out of reach of children. It is important to take the medication exactly as prescribed and not to stop or adjust the dose without consulting a healthcare professional. Regular heart rate monitoring is recommended during treatment to ensure safety. Patients should avoid abrupt changes in posture to reduce the risk of dizziness. Always inform your doctor about any other medications or health conditions before starting Ivabradine.

Avoid Interactions

  • Ivabradine can interact with several types of medications, including those that affect heart rhythm or are metabolized by the liver enzyme CYP3A4. Common interacting drugs include certain antibiotics, antifungals, calcium channel blockers, and some antidepressants. Grapefruit juice may also increase Ivabradine levels in the blood, so it is best to avoid it while taking this medication. Alcohol use should be limited, as it may enhance drowsiness or dizziness. Always review your current medications with a healthcare provider to avoid potential interactions.

Frequently Asked Questions

Ivabradine is used to lower heart rate in adults with chronic stable angina or heart failure with reduced ejection fraction.

It is taken orally twice daily with food, as prescribed by a healthcare provider. Do not adjust the dose without medical advice.

Some users may experience temporary brightness or halos in vision, especially when moving between light and dark areas.

It may interact with certain heart medications; always consult a healthcare provider before combining treatments.

Ivabradine is manufactured by Krka, D.D., Novo Mesto, and is of EU origin.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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