Product image of Ivermectin Pädia Gmbh (Ivermectin) supplied by GNH India

Ivermectin Pädia Gmbh

Active Ingredient:
Ivermectin
Origin:
EU

Ivermectin Pädia Gmbh (Ivermectin)

Ivermectin, the active ingredient in Ivermectin Pädia Gmbh, is an antiparasitic (macrocyclic lactone) presented as an oral formulation for systemic use. It is employed to treat a range of helminthic and ectoparasitic infections in both adults and children.
GNH India supplies Ivermectin Pädia Gmbh as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pädia Gmbh, De, Heppenheim

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Indications & Clinical Uses

Ivermectin acts on a variety of parasitic diseases by targeting the organisms' nervous system.

  • Strongyloidiasis: eliminates intestinal larvae and prevents autoinfection.
  • Onchocerciasis: kills microfilariae, reducing skin and ocular manifestations.
  • Scabies: eradicates Sarcoptes mites, relieving itching and skin lesions.
  • Lymphatic filariasis: reduces microfilarial load, helping to control transmission.

How It Works

  • Ivermectin binds selectively to glutamate‑gated chloride channels in invertebrate nerve and muscle cells. This binding increases chloride ion influx, causing hyperpolarization of the cell membrane, leading to paralysis and death of the parasite while having minimal effect on mammalian cells.

Side Effects

Ivermectin is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Dizziness: transient sensation of light‑headedness.
  • Nausea: mild to moderate upset stomach.
  • Diarrhea: loose stools occurring shortly after dosing.
  • Abdominal pain: cramp‑like discomfort.

Serious or Rare Side Effects

  • Severe skin reactions: including Stevens‑Johnson syndrome.
  • Hepatic injury: elevated liver enzymes or jaundice.
  • Visual disturbances: blurred vision or ocular pain.
  • Seizures: rare neurologic events, especially in patients with CNS disorders.
  • Anaphylaxis: acute allergic reaction requiring immediate medical attention.

Precautions & Warnings

Before prescribing Ivermectin, clinicians should consider several safety measures.

  • Contraindications: avoid in patients with known hypersensitivity to ivermectin or its excipients.
  • Liver function: monitor hepatic enzymes in patients with pre‑existing liver disease.
  • Central nervous system disorders: use cautiously in patients with a history of seizures or encephalopathy.
  • Drug interactions: review concomitant medications that may affect ivermectin metabolism.
  • Storage: Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ivermectin may interact with other medicines, requiring attention to potential effects.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampicin): may reduce ivermectin plasma concentrations.
  • Warfarin: concurrent use can increase bleeding risk.
  • Neurotoxic agents (e.g., levetiracetam): may potentiate neurotoxicity.

Moderate Interactions (Monitor Closely)

  • P‑gp inhibitors (e.g., verapamil): may raise ivermectin levels.
  • Other antiparasitics: combined use can increase the frequency of adverse gastrointestinal effects.

Frequently Asked Questions

Ivermectin Pädia Gmbh is indicated for the treatment of strongyloidiasis, onchocerciasis, scabies and lymphatic filariasis. In each case the drug targets the parasite’s nervous system, leading to paralysis and death of the organism, thereby resolving infection.

Ivermectin binds to glutamate‑gated chloride channels that are present in many invertebrates. This binding opens the channels, allowing an influx of chloride ions, which hyperpolarizes the cell membrane, causing paralysis and eventual death of the parasite while sparing human cells.

The specific dose of Ivermectin Pädia Gmbh is determined by the prescribing healthcare professional based on the patient’s age, weight, the indication being treated and local treatment guidelines. Only a qualified prescriber should set the dosing regimen.

Safety data for ivermectin in pregnancy and lactation are limited, and the product’s pregnancy category is not established. Use is generally avoided unless the potential benefit justifies the potential risk, and the decision should be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Ivermectin belongs to the macrocyclic lactone class and offers a broad spectrum against several nematodes and ectoparasites. Compared with older agents such as albendazole or topical permethrin, ivermectin provides a convenient oral route and often requires fewer doses, though choice depends on the specific infection and patient factors.

Ivermectin Pädia Gmbh should be stored at room temperature, below 25 °C, in its original packaging. The container should be kept tightly closed, protected from moisture and direct sunlight to maintain product stability.

The medication is taken orally, usually as a single dose or a short course depending on the indication. It may be swallowed with water and can be taken with or without food, unless the prescribing clinician advises otherwise.

Serious adverse events, although rare, include severe skin reactions such as Stevens‑Johnson syndrome, hepatic injury, visual disturbances, seizures and anaphylaxis. Patients should seek immediate medical attention if they experience any of these symptoms after taking the drug.

Ivermectin should not be used by individuals with a known hypersensitivity to the drug or its excipients. Caution is also advised for patients with severe liver disease, certain central nervous system disorders, or those taking medications that strongly interact with ivermectin.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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