Product image of Ivermectin Glenmark (Ivermectin) supplied by GNH India

Ivermectin Glenmark

Active Ingredient:
Ivermectin
Origin:
EU

Ivermectin Glenmark (Ivermectin)

Ivermectin, the active ingredient in Ivermectin Glenmark, is an anthelmintic presented as an oral tablet for oral use. It treats a range of parasitic infections in both adults and children, including river blindness, strongyloidiasis, filariasis, scabies, lice and other related conditions worldwide.

GNH India supplies Ivermectin Glenmark as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company ensures consistent quality and regulatory compliance across all shipments, and our distribution network reaches key markets in Europe, Asia, Africa and the Americas, facilitating reliable access for healthcare providers.

Manufacturer / TM Owner

Glenmark Arzneimittel Gmbh

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Indications & Clinical Uses

  • Ivermectin is an antiparasitic drug that targets a variety of helminth and ectoparasite infections.
  • Onchocerciasis: reduces microfilarial load and prevents disease progression.
  • Strongyloidiasis: eliminates intestinal larvae and prevents dissemination.
  • Lymphatic filariasis: decreases adult worm burden and reduces transmission.
  • Scabies: eradicates Sarcoptes scabiei mites, relieving itching and skin lesions.
  • Pediculosis: kills head lice and nits, controlling infestation.
  • Intestinal helminth infections: clears common roundworm and hookworm infections, improving gastrointestinal health.

How It Works

  • Ivermectin binds to glutamate‑gated chloride channels in the nerve and muscle cells of invertebrates. This activation increases chloride ion influx, causing hyperpolarization, paralysis, and eventual death of the parasite. The drug has minimal affinity for mammalian GABA receptors, limiting toxicity in humans at therapeutic doses.

Side Effects

Ivermectin may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea
  • Diarrhea
  • Abdominal pain
  • Dizziness
  • Headache
  • Pruritus

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome
  • Encephalopathy
  • Severe skin reactions
  • Hepatic injury
  • Visual disturbances
  • Anaphylaxis

Precautions & Warnings

  • When prescribing ivermectin, several safety considerations should be observed.
  • Pregnancy: safety not established; avoid unless benefit outweighs risk.
  • Breastfeeding: unknown; consider potential exposure to infant.
  • Liver disease: use with caution; monitor hepatic function.
  • Concomitant CNS depressants: may increase neurotoxicity risk.
  • Drug interactions: review all concomitant medications.
  • Store at ambient temperature: keep in original packaging, protect from moisture and light.

Avoid Interactions

Ivermectin can interact with other medicines, affecting its concentration or toxicity.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors: may increase ivermectin plasma levels.
  • Warfarin: potential enhancement of anticoagulant effect.
  • P‑glycoprotein inhibitors: increase systemic exposure.
  • Other antiparasitics: risk of additive toxicity.
  • Neuroactive GABAergic agents: heightened risk of neurotoxicity.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers: may reduce efficacy.
  • Antacids: may affect absorption.
  • Macrolide antibiotics: potential pharmacokinetic interaction.
  • Statins: monitor for muscle toxicity.
  • Antifungals (e.g., ketoconazole): may alter ivermectin levels.

Frequently Asked Questions

Ivermectin Glenmark is used to treat a range of parasitic infections, including onchocerciasis (river blindness), strongyloidiasis, lymphatic filariasis, scabies, pediculosis (lice infestation), and various intestinal helminth infections.

Ivermectin activates glutamate‑gated chloride channels in the nerve and muscle cells of parasites, causing an influx of chloride ions that hyperpolarizes the cells, leading to paralysis and death of the organism.

The appropriate dose of Ivermectin Glenmark is determined by the prescribing healthcare professional based on the specific indication, patient weight, age, and clinical condition. Dosage regimens are not standardized across all uses.

Safety of ivermectin in pregnancy has not been fully established, and it should only be used if the potential benefit justifies the potential risk. Data on breastfeeding are limited, so caution is advised and a risk‑benefit assessment should be performed.

To order Ivermectin Glenmark, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import documentation.

Ivermectin belongs to the macrocyclic lactone class and is distinguished by its activity against a broad spectrum of nematodes and ectoparasites. Compared with older agents such as albendazole or mebendazole, ivermectin often requires fewer doses and has a different safety profile, especially regarding neurotoxicity.

Ivermectin Glenmark should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture and direct sunlight to maintain stability.

Ivermectin Glenmark is administered orally, typically as a tablet that is swallowed with water. The exact method of administration, including whether it should be taken with food, is specified by the prescribing clinician.

Serious risks include rare but severe reactions such as Stevens‑Johnson syndrome, encephalopathy, significant hepatic injury, visual disturbances, and anaphylaxis. Patients should be monitored for any unusual symptoms and seek immediate medical attention if severe reactions occur.

Ivermectin Glenmark should not be used in individuals with known hypersensitivity to ivermectin or any excipients, in patients taking strong CYP3A4 inhibitors without medical supervision, and in those with certain neurological disorders where increased drug exposure could be harmful.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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