Product image of Ivermectin Medical Valley (Ivermectin) supplied by GNH India

Ivermectin Medical Valley

Active Ingredient:
Ivermectin
Origin:
EU

Ivermectin Medical Valley (Ivermectin)

Ivermectin, the active ingredient in Ivermectin Medical Valley, is an anthelmintic presented as a tablet for oral use. It treats a range of parasitic infections such as onchocerciasis, strongyloidiasis, scabies, pediculosis and other helminth infections in adults and children.

GNH India supplies Ivermectin Medical Valley as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Medical Valley Invest Ab

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Indications & Clinical Uses

Ivermectin is an antiparasitic agent used to treat infections caused by various helminths and ectoparasites.

  • Onchocerciasis: reduces microfilarial load and prevents disease progression.
  • Strongyloidiasis: eradicates intestinal Strongyloides stercoralis infection.
  • Scabies: eliminates Sarcoptes scabiei mites and resolves skin lesions.
  • Pediculosis: kills head lice and nits, stopping infestation spread.
  • Other helminth infections: provides broad-spectrum activity against multiple nematode species.

How It Works

  • Ivermectin binds selectively to glutamate‑gated chloride channels in the nerve and muscle cells of invertebrates. This binding increases chloride ion influx, causing hyperpolarization of the cell membrane, leading to paralysis and death of the parasite while sparing mammalian cells due to the absence of these channels in humans.

Side Effects

Ivermectin is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Dizziness: transient feeling of light‑headedness.
  • Nausea: mild to moderate upset stomach.
  • Diarrhea: loose stools occurring shortly after dosing.
  • Abdominal pain: cramping or discomfort in the stomach area.
  • Pruritus: itching sensation, often related to parasite die‑off.
  • Headache: mild to moderate tension‑type headache.

Serious or Rare Side Effects

  • Severe skin reactions: including rash or Stevens‑Johnson syndrome.
  • Hepatotoxicity: elevated liver enzymes or liver injury.
  • Visual disturbances: blurred vision or optic neuritis.
  • Seizures: rare neurologic events, especially in high doses.
  • Anaphylaxis: acute allergic reaction requiring emergency care.
  • Cardiovascular collapse: hypotension or shock in extreme cases.

Precautions & Warnings

Before prescribing Ivermectin, consider patient‑specific factors and safety measures.

  • Pregnancy: safety not established; avoid unless benefits outweigh potential risks.
  • Breastfeeding: unknown excretion in milk; consider discontinuation or monitor infant.
  • Renal or hepatic impairment: use with caution and adjust dose if necessary.
  • Concomitant medications: review for potential interactions, especially CYP3A4 inhibitors.
  • Pediatric use: dosing must be determined by a qualified prescriber.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Ivermectin may interact with other medicines; some require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase ivermectin plasma concentrations.
  • P‑glycoprotein inhibitors (e.g., verapamil, quinidine): can raise systemic exposure.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential enhancement of anticoagulant effect, monitor INR.
  • Other antiparasitics: may increase gastrointestinal side effects.
  • CNS depressants (e.g., benzodiazepines): may potentiate dizziness or sedation.
  • Statins metabolized by CYP3A4: monitor for muscle toxicity.
  • Antiepileptic drugs: may alter seizure threshold, observe clinical response.

Frequently Asked Questions

Ivermectin Medical Valley is prescribed for several parasitic infections, including onchocerciasis (river blindness), strongyloidiasis, scabies, pediculosis (lice infestation), and a variety of other helminth infections. It works by targeting the parasites directly, helping to eliminate the infection and relieve associated symptoms.

Ivermectin binds to glutamate‑gated chloride channels that are present in the nerve and muscle cells of invertebrate parasites. This binding opens the channels, allowing an influx of chloride ions, which hyperpolarizes the cells, leading to paralysis and death of the parasite while sparing human cells that lack these channels.

The dose of Ivermectin Medical Valley is determined by the prescribing clinician based on the specific infection, patient weight, age, and clinical condition. Dosage regimens vary for different indications and should be individualized according to professional medical guidance.

Safety data for ivermectin in pregnancy are limited, and the drug is classified as having an unknown risk. It should only be used if the potential benefit justifies the potential risk to the fetus. Likewise, because excretion in breast milk is not well defined, breastfeeding mothers should discuss risks and benefits with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Ivermectin offers a broad spectrum of activity against many nematodes and ectoparasites, often with a single oral dose, which can be more convenient than multi‑day regimens required for some alternatives. Compared with drugs like albendazole or metronidazole, ivermectin may have fewer gastrointestinal side effects but shares similar interaction potential with CYP3A4‑modulating agents.

Ivermectin Medical Valley should be stored at ambient temperature below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability throughout its shelf life.

The medication is taken orally, usually as a tablet swallowed with water. The exact administration schedule—whether a single dose or a repeat dose—depends on the indication and the prescriber’s instructions. Patients should follow the dosing guidance provided by their healthcare professional.

Serious adverse events, though rare, can include severe skin reactions such as Stevens‑Johnson syndrome, hepatotoxicity, visual disturbances, seizures, and anaphylaxis. Patients should seek immediate medical attention if they experience rash, jaundice, vision changes, seizures, or signs of an allergic reaction after taking the drug.

Ivermectin Medical Valley is contraindicated in individuals with known hypersensitivity to ivermectin or any of the product’s excipients. Caution is also advised for patients with severe hepatic impairment, those taking strong CYP3A4 inhibitors, and pregnant or breastfeeding women unless the benefits clearly outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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