Product image of Ivermectin Medical Valley (Ivermectin) supplied by GNH India

Ivermectin Medical Valley

Active Ingredient:
Ivermectin
Origin:
EU

Ivermectin Medical Valley (Ivermectin)

Ivermectin, the active ingredient in Ivermectin Medical Valley, is an anthelmintic (macrocyclic lactone) presented as an oral tablet for oral use. It treats a range of parasitic infections in humans, including onchocerciasis, strongyloidiasis, lymphatic filariasis, scabies and pediculosis.

GNH India supplies Ivermectin Medical Valley as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Medical Valley Invest Ab

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Indications & Clinical Uses

Ivermectin is an anthelmintic that targets parasitic helminths and ectoparasites.

  • Onchocerciasis: reduces microfilarial load and prevents disease progression.
  • Strongyloidiasis: eradicates intestinal Strongyloides stercoralis infection.
  • Lymphatic filariasis: eliminates adult worms and microfilariae to interrupt transmission.
  • Scabies: kills Sarcoptes scabiei mites, relieving itching and skin lesions.
  • Pediculosis: eliminates head lice infestations.

How It Works

  • Ivermectin binds selectively to glutamate‑gated chloride channels found in invertebrate nerve and muscle cells. This binding increases chloride ion influx, causing hyperpolarization of the cell membrane, leading to paralysis and death of the parasite while having minimal effect on mammalian cells.

Side Effects

Ivermectin may cause adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Diarrhea: loose stools.
  • Dizziness: transient light‑headedness.
  • Pruritus: skin itching.

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome: severe skin reaction.
  • Hepatotoxicity: elevated liver enzymes or liver injury.
  • Neurologic toxicity: seizures, ataxia, or altered consciousness.
  • Severe hypotension: sudden drop in blood pressure.

Precautions & Warnings

When prescribing ivermectin, consider the following precautions.

  • Pregnancy: safety not established; avoid unless benefit outweighs risk.
  • Breastfeeding: unknown; consider risk vs benefit.
  • Concomitant CNS depressants: may enhance neurotoxicity.
  • Liver impairment: use with caution; monitor hepatic function.
  • Drug interactions: review concomitant medications for potential interactions.
  • Store at ambient temperature: keep below 25 °C, retain original packaging, protect from moisture.

Avoid Interactions

Ivermectin can interact with other medicines; interactions are grouped by clinical significance.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine): may reduce ivermectin exposure.
  • P‑glycoprotein inhibitors (e.g., verapamil, quinidine): may increase ivermectin levels and risk of neurotoxicity.

Moderate Interactions (Monitor Closely)

  • Anticoagulants (e.g., warfarin): monitor INR as ivermectin may affect clotting.
  • Other antiparasitics (e.g., albendazole): assess additive toxicity.
  • CNS active drugs (e.g., benzodiazepines): observe for enhanced sedation.

Frequently Asked Questions

Ivermectin Medical Valley is prescribed to treat several parasitic infections, including onchocerciasis (river blindness), strongyloidiasis, lymphatic filariasis, scabies, and pediculosis (lice infestation). It works by eliminating the parasites responsible for these diseases, helping to relieve symptoms and prevent complications.

Ivermectin binds to glutamate‑gated chloride channels that are present in the nerve and muscle cells of many invertebrates. This binding opens the channels, allowing an influx of chloride ions, which hyperpolarizes the cells, leading to paralysis and death of the parasite while sparing human cells.

The dose of Ivermectin Medical Valley is determined by the prescribing healthcare professional based on the specific infection, patient weight, and clinical guidelines. Patients should follow the exact dosing instructions provided by their prescriber and not adjust the dose on their own.

Safety data for ivermectin in pregnancy and lactation are limited. It is generally advised to avoid use unless the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers should evaluate each case individually.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Ivermectin Medical Valley. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Ivermectin belongs to the macrocyclic lactone class and is often preferred for its broad spectrum against both helminths and ectoparasites. Compared with drugs like albendazole, ivermectin may have a more rapid effect on certain parasites such as scabies mites, but the choice depends on the specific infection, resistance patterns, and patient factors.

Ivermectin Medical Valley should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

The medication is taken orally, usually as a single tablet or a short course, depending on the indication. It should be swallowed with water on an empty stomach or as directed by the prescriber to maximize absorption.

Serious adverse events, though rare, can include severe skin reactions such as Stevens‑Johnson syndrome, hepatotoxicity, neurologic toxicity (e.g., seizures, ataxia), and sudden hypotension. Patients should seek immediate medical attention if they experience any of these symptoms.

Ivermectin should be avoided in individuals with known hypersensitivity to the drug, in patients with severe liver disease without careful monitoring, and in pregnant women unless the benefit justifies the risk. It is also contraindicated when taken with certain strong CYP3A4 inducers or P‑glycoprotein inhibitors that could lead to dangerous drug levels.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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