Product image of Ivermectin Orifarm Healthcare (Ivermectin) supplied by GNH India

Ivermectin Orifarm Healthcare

Active Ingredient:
Ivermectin
Origin:
EU

Ivermectin Orifarm Healthcare (Ivermectin)

Ivermectin, the active ingredient in Ivermectin Orifarm Healthcare, is an anthelmintic presented as a tablet for oral use. It treats parasitic worm infections and certain ectoparasitic conditions in humans.\n\nGNH India supplies Ivermectin Orifarm Healthcare as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Orifarm Healthcare A/S

1
Pack/s
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Indications & Clinical Uses

  • Ivermectin is an antiparasitic agent used to treat a range of helminth and ectoparasite infections.\n\n- Strongyloidiasis: eliminates intestinal Strongyloides stercoralis larvae and adult worms.\n- Onchocerciasis: reduces microfilarial load of Onchocerca volvulus, helping control river blindness.\n- Scabies: eradicates Sarcoptes scabiei mites, relieving skin infestation.\n- Lymphatic filariasis: decreases microfilariae of Wuchereria bancrofti, contributing to disease control.\n- Other helminth infections: targets various nematodes such as hookworms and pinworms.

How It Works

  • Ivermectin binds selectively to glutamate‑gated chloride channels in the nerve and muscle cells of invertebrates. This increases chloride ion influx, hyperpolarizing the cell membrane, which leads to paralysis and death of the parasite while having minimal effect on mammalian cells.

Side Effects

  • Adverse reactions may vary in frequency and severity.\n\nCommon Side Effects:\n- Dizziness: transient sensation of light‑headedness.\n- Nausea: mild to moderate stomach upset.\n- Diarrhea: loose stools occurring shortly after dosing.\n- Headache: mild to moderate pain in the head region.\n\nSerious or Rare Side Effects:\n- Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.\n- Hepatic dysfunction: elevated liver enzymes or jaundice.\n- Anaphylaxis: acute, potentially life‑threatening allergic response.

Precautions & Warnings

  • Before prescribing Ivermectin, consider the following safety measures.\n\n- Assess for Loa loa infection: avoid use in patients with high microfilaremia due to risk of severe reactions.\n- Monitor liver function: check baseline hepatic enzymes in patients with liver disease.\n- Avoid in known hypersensitivity: discontinue if allergic signs appear.\n- Use caution in pregnancy: weigh benefits against potential risks.\n- Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

  • Ivermectin may interact with other medicines; review patient medication lists.\n\nMajor Interactions (Avoid):\n- Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase ivermectin plasma levels.\n- P‑glycoprotein inhibitors (e.g., verapamil): can raise systemic exposure.\n\nModerate Interactions (Monitor Closely):\n- Warfarin: potential for enhanced anticoagulant effect, monitor INR.\n- Statins (e.g., simvastatin): increased risk of myopathy, observe muscle symptoms.\n- Antiepileptic drugs (e.g., carbamazepine): may reduce ivermectin efficacy.

Frequently Asked Questions

Ivermectin Orifarm Healthcare is prescribed to treat parasitic infections such as strongyloidiasis, onchocerciasis, scabies, lymphatic filariasis, and other helminth infections. It works by targeting the parasites’ nervous system, leading to their paralysis and death.

Ivermectin binds to glutamate‑gated chloride channels in invertebrate nerve and muscle cells, increasing chloride ion flow. This hyperpolarizes the cells, causing paralysis and eventual death of the parasite while sparing human cells.

The dosage of Ivermectin Orifarm Healthcare is determined by the prescribing clinician based on the specific infection, patient weight, and clinical guidelines. Patients should follow the prescriber’s instructions exactly.

Safety data for ivermectin in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ivermectin is a broad‑spectrum antiparasitic with a unique mechanism targeting glutamate‑gated chloride channels, which differs from drugs like albendazole that inhibit microtubule formation. This distinction can affect efficacy, safety profile, and drug‑interaction potential, making ivermectin a preferred option for certain infections.

Store the tablets at room temperature, below 25 °C, in the original packaging. Protect them from moisture, excessive heat and direct sunlight to maintain product stability.

Ivermectin Orifarm Healthcare is taken orally, usually with water. The exact administration schedule, including whether it should be taken with food, is determined by the prescribing clinician.

Serious risks include severe skin reactions such as Stevens‑Johnson syndrome, hepatic dysfunction, and rare anaphylactic reactions. Patients should seek immediate medical attention if they experience rash, jaundice, or signs of an allergic response.

Ivermectin should be avoided in individuals with known hypersensitivity to the drug, those with high Loa loa microfilaremia, and patients in whom the prescriber determines the risks outweigh the benefits, such as certain pregnant or severely ill patients.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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