Product image of Ivermectin Stada (Ivermectin) supplied by GNH India

Ivermectin Stada

Active Ingredient:
Ivermectin
Origin:
EU

Ivermectin Stada (Ivermectin)

Ivermectin, the active ingredient in Ivermectin Stada, is a macrocyclic lactone anthelmintic presented as an oral tablet for oral use. It treats parasitic infections such as onchocerciasis, strongyloidiasis, scabies, lymphatic filariasis and other intestinal helminth infections.

GNH India supplies Ivermectin Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Gmbh

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Indications & Clinical Uses

Ivermectin is an antiparasitic agent used to treat a range of helminth and ectoparasite infections.

  • Onchocerciasis: reduces microfilarial load and helps prevent disease progression.
  • Strongyloidiasis: eliminates intestinal larvae and prevents systemic dissemination.
  • Scabies: eradicates Sarcoptes scabiei mites, relieving skin lesions.
  • Lymphatic filariasis (in combination therapy): contributes to parasite clearance and transmission interruption.
  • Other intestinal helminth infections: broad‑spectrum activity against various nematodes.

How It Works

  • Ivermectin binds selectively to glutamate‑gated chloride channels in parasites, increasing chloride ion influx. This hyperpolarizes neuronal and muscular membranes, causing paralysis and death of the parasite without affecting mammalian cells, which lack these specific channels.

Side Effects

Ivermectin is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Dizziness: transient feeling of light‑headedness.
  • Nausea: mild to moderate upset stomach.
  • Diarrhea: loose stools during treatment.
  • Abdominal pain: cramping or discomfort.
  • Pruritus: itching at the site of infection.
  • Headache: mild to moderate tension.

Serious or Rare Side Effects

  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatotoxicity: elevated liver enzymes or hepatitis.
  • Neurologic effects: seizures, ataxia, or altered consciousness.
  • Anaphylaxis: acute allergic response requiring emergency care.
  • Vision changes: blurred vision or optic neuritis.
  • Cardiac arrhythmias: rare conduction disturbances.

Precautions & Warnings

Before prescribing Ivermectin Stada, consider the following precautions.

  • Assess liver function: evaluate hepatic status as metabolism is hepatic.
  • Review concomitant medications: avoid drugs that may increase ivermectin exposure.
  • Monitor for neurologic symptoms: especially in patients with blood‑brain barrier disorders.
  • Use with caution in the elderly: increased susceptibility to adverse effects.
  • Pregnancy and lactation: safety not established; weigh benefits against risks.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Ivermectin may interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Warfarin: may potentiate anticoagulant effect, increasing bleeding risk.
  • Carbamazepine: induces metabolism, reducing ivermectin plasma levels.
  • Erythromycin: can raise ivermectin concentrations, heightening toxicity.

Moderate Interactions (Monitor Closely)

  • Ketoconazole and other azole antifungals: may increase ivermectin exposure.
  • Phenytoin: may lower ivermectin levels, reducing efficacy.
  • P‑glycoprotein inhibitors (e.g., verapamil): can raise systemic concentrations.
  • Antiretroviral agents (e.g., ritonavir): may alter ivermectin metabolism.
  • St. John’s wort: may decrease ivermectin exposure through enzyme induction.

Frequently Asked Questions

Ivermectin Stada is prescribed to treat a range of parasitic infections, including onchocerciasis (river blindness), strongyloidiasis, scabies, lymphatic filariasis (as part of combination therapy), and various intestinal helminth infections. It works by eliminating the parasites responsible for these conditions.

Ivermectin binds to glutamate‑gated chloride channels that are present in many parasites. This binding opens the channels, allowing an influx of chloride ions, which hyperpolarizes the parasite’s nerve and muscle cells, leading to paralysis and death of the organism while sparing human cells.

The dosage of Ivermectin Stada is determined by the prescribing clinician based on the specific infection, patient weight, age, and clinical condition. No fixed regimen is provided here; the prescriber will calculate the appropriate dose and schedule.

Safety data for Ivermectin Stada in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the prescriber should assess each case individually.

To order Ivermectin Stada, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Ivermectin offers a broad spectrum of activity against both nematodes and ectoparasites, often requiring fewer doses than alternatives such as albendazole or mebendazole. While albendazole is effective for many intestinal worms, ivermectin is preferred for onchocerciasis, strongyloidiasis, and scabies due to its unique mechanism and high efficacy in those indications.

Ivermectin Stada should be stored at ambient temperature below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Ivermectin Stada is administered orally as a tablet. It should be swallowed whole with a glass of water, and can be taken with or without food unless the prescriber advises otherwise. The exact timing and frequency depend on the condition being treated and the dose prescribed.

Serious adverse events, although rare, include severe skin reactions such as Stevens‑Johnson syndrome, hepatotoxicity, neurologic effects like seizures or ataxia, anaphylaxis, and significant visual disturbances. Patients should seek immediate medical attention if they experience any of these symptoms.

Ivermectin Stada is contraindicated in patients with known hypersensitivity to ivermectin or any excipients in the formulation. Caution is also advised for individuals with compromised blood‑brain barriers, severe liver disease, or those taking medications that strongly interact with ivermectin. The prescriber will evaluate suitability on a case‑by‑case basis.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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