Product image of Ivermectin Stada (Ivermectin) supplied by GNH India

Ivermectin Stada

Active Ingredient:
Ivermectin
Origin:
EU

Ivermectin Stada (Ivermectin)

Ivermectin, the active ingredient in Ivermectin Stada, is an anthelmintic (macrocyclic lactone) presented as an oral formulation for oral use. It treats a range of parasitic infections in humans, including strongyloidiasis, onchocerciasis, scabies, lice infestations and other helminth infections.

GNH India supplies Ivermectin Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

  • Ivermectin is an anthelmintic that targets parasitic infections.
  • Strongyloidiasis: eliminates the intestinal worm Strongyloides stercoralis.
  • Onchocerciasis (river blindness): reduces microfilarial load and prevents disease progression.
  • Scabies: eradicates Sarcoptes scabiei mites causing crusted and ordinary scabies.
  • Lice infestations: eliminates head and body lice.
  • Other helminth infections: treats various nematode infections such as ascariasis and hookworm.

How It Works

  • Ivermectin binds selectively to glutamate‑gated chloride channels in invertebrate nerve and muscle cells, increasing chloride ion influx, which hyperpolarises the cell membrane, leading to paralysis and death of the parasite. It also interferes with GABA‑mediated neurotransmission in some parasites, further contributing to immobilisation while mammalian cells lack these channels, providing a wide safety margin.

Side Effects

Ivermectin may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea
  • Diarrhoea
  • Dizziness
  • Skin rash

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome or other severe skin reactions
  • Seizures or encephalopathy
  • Hepatotoxicity

Precautions & Warnings

  • Before prescribing Ivermectin, clinicians should consider several safety aspects.
  • Assess for contraindications: avoid in patients with known hypersensitivity to ivermectin or other macrocyclic lactones.
  • Evaluate infection severity: use with caution in patients with high parasite burden to reduce risk of severe inflammatory reactions.
  • Consider co‑morbidities: monitor liver function in patients with hepatic impairment.
  • Pregnancy and lactation: use only if the benefit outweighs the risk; consult the prescriber.
  • Drug interactions: review concomitant medications, especially those affecting CYP3A4.
  • Store at ambient temperature: keep below 25°C, retain in the original packaging, and protect from moisture and light.

Avoid Interactions

Ivermectin can interact with several medicines, requiring careful review.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole) may increase ivermectin plasma levels.
  • P‑glycoprotein inhibitors (e.g., verapamil) may raise exposure.
  • Co‑administration with other neurotoxic agents (e.g., benzimidazoles) may increase neurotoxicity risk.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampicin) may reduce efficacy.
  • Anticoagulants (e.g., warfarin) may have altered effect.
  • Anticonvulsants (e.g., carbamazepine) may affect seizure threshold.

Frequently Asked Questions

Ivermectin Stada is prescribed to treat a variety of parasitic infections, including strongyloidiasis, onchocerciasis (river blindness), scabies, lice infestations and other helminthic diseases. It works by targeting the parasites responsible for these conditions, helping to eliminate the infection and relieve associated symptoms.

Ivermectin binds to glutamate‑gated chloride channels that are present in the nerve and muscle cells of parasites. This binding opens the channels, allowing an influx of chloride ions, which hyperpolarises the cells, causing paralysis and eventual death of the parasite. Mammalian cells lack these specific channels, which limits toxicity to humans.

The dose of Ivermectin Stada is determined by the prescribing clinician based on the specific indication, the patient’s weight, age and overall health status. Dosage regimens vary for conditions such as strongyloidiasis, onchocerciasis or scabies, and the prescriber will provide exact instructions tailored to the individual patient.

Safety data for ivermectin use in pregnancy and lactation are limited. The drug should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers will assess each case individually and may recommend alternative therapies if safety concerns arise.

To order Ivermectin Stada, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details and any required import documentation.

Ivermectin belongs to the macrocyclic lactone class and is distinguished by its activity against a broad range of nematodes and ectoparasites. Compared with benzimidazoles such as albendazole, ivermectin often requires fewer doses and has a different safety profile, making it preferable for certain infections like onchocerciasis and scabies.

Ivermectin Stada should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging to protect it from moisture and light. Do not store in extreme heat or humidity, and ensure the container is tightly closed when not in use.

Ivermectin Stada is administered orally. The tablet or capsule is taken with a full glass of water, preferably on an empty stomach unless the prescriber advises otherwise. The exact timing and any dietary considerations will be outlined in the prescribing information provided by the healthcare professional.

Serious adverse reactions, although rare, include severe skin reactions such as Stevens‑Johnson syndrome, neurological events like seizures or encephalopathy, and liver toxicity. Patients should be monitored closely for any signs of these conditions, and treatment should be discontinued immediately if they occur.

Ivermectin Stada should not be used by individuals with a known hypersensitivity to ivermectin or other macrocyclic lactones. Caution is also advised for patients with severe hepatic impairment, pregnant women unless the benefit justifies the risk, and those taking strong CYP3A4 inhibitors without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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