Ivermectina Cantabria (Ivermectin)

Ivermectin acts on a range of parasitic diseases by targeting the parasite's nervous system.

• Onchocerciasis: reduces microfilarial load and helps prevent disease progression.
• Strongyloidiasis: eliminates intestinal larvae and prevents disseminated infection.
• Scabies: kills the Sarcoptes scabiei mite, relieving itching and skin lesions.
• Lice infestations: eradicates head and body lice, stopping further spread.
• Other intestinal helminth infections: clears various worm species from the gastrointestinal tract.

• Ivermectin binds to glutamate‑gated chloride channels in invertebrate nerve and muscle cells, increasing chloride ion permeability. This hyperpolarizes the cells, leading to paralysis and death of the parasite while having minimal effect on mammalian cells.

Ivermectin is generally well tolerated, but adverse reactions can occur.

Common Side Effects

• Nausea: mild to moderate stomach upset.
• Diarrhea: loose stools during treatment.
• Dizziness: transient light‑headedness.
• Pruritus: mild skin itching.
• Headache: occasional mild headache.
• Fatigue: feeling of tiredness.

Serious or Rare Side Effects

• Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
• Neurological events: seizures, encephalopathy, or ataxia.
• Hepatotoxicity: elevated liver enzymes or jaundice.
• Hypotension: sudden drop in blood pressure.
• Anaphylaxis: rare allergic reaction requiring immediate medical attention.

Before using Ivermectina Cantabria, consider the following safety measures.

• Pregnancy: consult a healthcare professional; safety data are limited.
• Breastfeeding: discuss risks with a physician, as drug may pass into milk.
• Liver disease: dose may need adjustment in hepatic impairment.
• Drug interactions: review concomitant medications with a pharmacist.
• Renal impairment: monitor kidney function if present.
• Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Ivermectin may interact with other medicines; monitor accordingly.

Major Interactions (Avoid)

• Warfarin: increased anticoagulant effect, risk of bleeding.
• Cyclosporine: heightened neurotoxicity risk.
• Benzodiazepines: enhanced central nervous system depression.

Moderate Interactions (Monitor Closely)

• Macrolide antibiotics (e.g., erythromycin): may increase ivermectin plasma levels.
• Anticonvulsants (e.g., carbamazepine): may reduce efficacy.
• St. John’s Wort: possible reduction in drug concentration.