Product image of Ivermectina Teva (Ivermectin) supplied by GNH India

Ivermectina Teva

Active Ingredient:
Ivermectin
Origin:
EU

Ivermectina Teva (Ivermectin)

Ivermectin, the active ingredient in Ivermectina Teva, is an antiparasitic (macrocyclic lactone) presented as an oral formulation for systemic use. It is employed to treat a range of parasitic infections, including river blindness, strongyloidiasis, scabies, lice infestation and other helminthic diseases in appropriate patient populations.

GNH India supplies Ivermectina Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Ivermectin is an antiparasitic agent that acts on a variety of helminth and ectoparasite infections.

  • Onchocerciasis: reduces microfilarial load and helps prevent ocular damage.
  • Strongyloidiasis: eliminates intestinal larvae and prevents disseminated disease.
  • Scabies: eradicates Sarcoptes scabiei mites, relieving skin lesions.
  • Pediculosis: kills head‑lice and nits, stopping infestation spread.
  • Other helminth infections: provides broad‑spectrum activity against several nematodes.

How It Works

  • Ivermectin binds selectively to glutamate‑gated chloride channels in the nerve and muscle cells of invertebrates. This binding increases chloride ion influx, causing hyperpolarization of the cell membrane, which leads to paralysis and eventual death of the parasite. The drug shows minimal affinity for mammalian chloride channels, contributing to its safety profile when used as directed.

Side Effects

Ivermectin is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Dizziness: transient light‑headedness.
  • Pruritus: itching at the site of parasite death.
  • Headache: mild tension‑type pain.
  • Abdominal pain: cramping or discomfort.
  • Diarrhea: loose stools.

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome: severe skin reaction requiring immediate care.
  • Hepatic injury: elevated liver enzymes or jaundice.
  • Neurologic toxicity: seizures, ataxia, or altered mental status.
  • Anaphylaxis: acute allergic response with respiratory compromise.
  • Vision changes: blurred vision or optic neuritis.
  • Severe skin rash: extensive erythema or bullous lesions.

Precautions & Warnings

Before prescribing Ivermectina Teva, clinicians should consider several safety measures.

  • Assess hypersensitivity: confirm no known allergy to ivermectin or excipients.
  • Evaluate liver function: use caution in patients with hepatic impairment.
  • Review concomitant CNS drugs: avoid additive neurotoxicity.
  • Consider pregnancy status: weigh benefits against potential risks.
  • Monitor for drug‑induced skin reactions: educate patients on warning signs.
  • Store at room temperature below 25°C: keep in the original packaging, protect from moisture and light.

Avoid Interactions

Ivermectin may interact with other medicines, requiring attention to dosage and monitoring.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): may increase ivermectin plasma levels.
  • P‑gp inhibitors (e.g., verapamil, quinidine): can raise systemic exposure.
  • Co‑administration with other neurotoxic antiparasitics: risk of additive CNS effects.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential for enhanced anticoagulant effect.
  • CNS depressants (e.g., benzodiazepines, opioids): monitor for excessive sedation.
  • Antifungal azoles (non‑CYP3A4): may modestly affect metabolism.

Frequently Asked Questions

Ivermectina Teva contains ivermectin, which is indicated for the treatment of onchocerciasis (river blindness), strongyloidiasis, scabies, pediculosis (lice infestation) and a range of other helminth infections. The drug works by targeting the parasites responsible for these diseases, helping to eliminate them and alleviate associated symptoms.

Ivermectin binds to glutamate‑gated chloride channels that are present in the nerve and muscle cells of many invertebrates. This binding opens the channels, allowing an influx of chloride ions, which hyperpolarizes the cells, leading to paralysis and death of the parasite. Human cells lack these specific channels, which contributes to the drug’s selective toxicity.

The dosage of Ivermectina Teva is determined by the prescribing clinician based on the specific indication, patient weight, age, and clinical condition. Healthcare providers follow established guidelines and adjust the regimen as needed for optimal efficacy and safety.

Safety data for ivermectin in pregnancy and lactation are limited. The drug should only be used when the potential benefit justifies any possible risk to the fetus or infant. Clinicians should discuss individual circumstances with patients and consider alternative therapies when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Ivermectin offers a broad spectrum of activity against many nematodes and ectoparasites, often with a single oral dose, which can be advantageous over drugs that require multiple administrations. Compared with alternatives such as albendazole or permethrin, ivermectin may have a different safety profile and specific efficacy for conditions like onchocerciasis and strongyloidiasis.

Ivermectina Teva should be stored at room temperature below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Ivermectina Teva is taken orally, usually with water. The exact administration schedule—whether a single dose or a repeat dose—depends on the indication and the prescriber’s instructions. Patients should follow the healthcare professional’s guidance regarding timing and any required fasting.

Serious adverse events, though rare, can include severe skin reactions such as Stevens‑Johnson syndrome, hepatic injury, neurologic toxicity (e.g., seizures or altered mental status), and anaphylaxis. Patients should seek immediate medical attention if they experience rash, jaundice, neurological symptoms, or signs of an allergic reaction.

Ivermectina Teva is contraindicated in individuals with a known hypersensitivity to ivermectin or any of its excipients. Caution is also advised for patients with severe hepatic impairment, certain neurological disorders, or those taking medications that strongly inhibit CYP3A4 or P‑gp without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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