Product image of Ivermectine Glenmark (Ivermectin) supplied by GNH India

Ivermectine Glenmark

Active Ingredient:
Ivermectin
Origin:
EU

Ivermectine Glenmark (Ivermectin)

Ivermectin, the active ingredient in Ivermectine Glenmark, is an anthelmintic presented as an oral formulation for systemic use. It is employed to treat a range of parasitic worm infections and ectoparasitic conditions in adults and children as prescribed by a healthcare professional.

GNH India supplies Ivermectine Glenmark as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides full regulatory documentation to support export across multiple regions and ensures timely delivery.

Manufacturer / TM Owner

Glenmark Arzneimittel Gmbh

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Indications & Clinical Uses

Ivermectin is an antiparasitic agent used to treat infections caused by various helminths and ectoparasites.

  • Onchocerciasis: reduces microfilarial load and helps control river blindness.
  • Strongyloidiasis: eliminates intestinal Strongyloides stercoralis infection.
  • Scabies: eradicates Sarcoptes scabiei infestation and relieves itching.
  • Lymphatic filariasis: decreases microfilariae and contributes to disease control programs.
  • Other helminth infections: treats a variety of soil‑transmitted nematode infections such as ascariasis and hookworm.

How It Works

  • Ivermectin binds selectively to glutamate‑gated chloride channels found in the nerve and muscle cells of parasites. This binding increases the permeability of the membrane to chloride ions, causing hyperpolarization, paralysis, and ultimately death of the organism. The drug has low affinity for mammalian receptors, which limits toxicity in humans. It is metabolized primarily in the liver and excreted in feces, providing a prolonged antiparasitic effect after a single dose.

Side Effects

Ivermectin may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Dizziness
  • Nausea
  • Diarrhea

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome or other severe skin reactions
  • Hepatotoxicity with elevated liver enzymes
  • Neurological events such as seizures or altered consciousness

Precautions & Warnings

When prescribing Ivermectine Glenmark, healthcare professionals should consider several precautionary measures to ensure safe use.

  • Assess for known hypersensitivity: avoid in patients with documented allergy to ivermectin.
  • Evaluate liver function: monitor hepatic enzymes in patients with pre‑existing liver disease.
  • Use cautiously in CNS disorders: consider risk of neurotoxicity in patients with compromised blood‑brain barrier.
  • Review concomitant P‑glycoprotein inhibitors: dose adjustment may be required.
  • Pregnancy and lactation: weigh potential benefits against unknown risks before use.
  • Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ivermectin can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Strong P‑glycoprotein inhibitors (e.g., clarithromycin, cyclosporine): may increase ivermectin plasma levels.
  • Co‑administration with other neurotoxic agents (e.g., benzimidazoles) in patients with CNS disease: heightened risk of neurotoxicity.

Moderate Interactions (Monitor Closely)

  • CYP3A4 substrates (e.g., azole antifungals, some antiretrovirals): may affect metabolism.
  • Anticoagulants (e.g., warfarin): monitor INR as ivermectin may potentiate effect.
  • Antihistamines or corticosteroids used for allergic reactions: monitor for enhanced sedation or skin reactions.

Frequently Asked Questions

Ivermectine Glenmark contains ivermectin, an antiparasitic medication indicated for the treatment of onchocerciasis, strongyloidiasis, scabies, lymphatic filariasis and a range of other helminth infections. It is prescribed by qualified health professionals to eliminate the causative parasites.

Ivermectin acts by binding to glutamate‑gated chloride channels in the nerve and muscle cells of parasites. This increases chloride ion flow, leading to hyperpolarisation, paralysis and death of the parasite while having minimal activity on equivalent human receptors.

The appropriate dose of Ivermectine Glenmark is determined by the prescribing clinician based on the specific indication, patient weight, age, severity of infection and any relevant comorbidities. No fixed regimen is provided here; the prescriber sets the exact dosage.

Safety data for ivermectin in pregnancy and lactation are limited. The product is classified as pregnancy category unknown, so clinicians must weigh potential benefits against possible risks before prescribing to pregnant or nursing women.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ivermectin offers a broad spectrum of activity against many nematodes and ectoparasites with a single oral dose in many cases, which can be an advantage over drugs requiring multiple doses or parenteral administration. Its safety profile is generally favourable, though specific alternatives may be preferred for certain infections or patient populations.

Store Ivermectine Glenmark below 25 °C in its original packaging, protecting it from moisture, direct sunlight and excessive heat. Maintaining these conditions helps preserve potency and ensures the product remains stable throughout its shelf‑life.

Ivermectine Glenmark is supplied as an oral formulation. It should be taken by mouth with water, following the dosage and timing prescribed by the treating physician. Food may be taken with or without the dose unless otherwise directed.

Serious adverse events, although rare, include severe skin reactions such as Stevens‑Johnson syndrome, hepatotoxicity manifested by elevated liver enzymes, and neurological complications like seizures or altered consciousness. Patients should seek immediate medical attention if any of these symptoms develop.

Ivermectine Glenmark should be avoided in individuals with a known hypersensitivity to ivermectin or any excipients in the formulation. Caution is also advised for patients with severe liver disease, compromised blood‑brain barrier, or those taking strong P‑glycoprotein inhibitors, unless a prescriber decides otherwise.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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