Product image of Ivermectine Pierre Fabre (Ivermectin) supplied by GNH India

Ivermectine Pierre Fabre

Active Ingredient:
Ivermectin
Origin:
EU

Ivermectine Pierre Fabre (Ivermectin)

Ivermectin, the active ingredient in Ivermectine Pierre Fabre, is an anthelmintic presented as an oral dosage form for systemic use. It is employed to treat a range of parasitic infections, including onchocerciasis, strongyloidiasis, scabies, lymphatic filariasis and other helminthic diseases in both adults and children as prescribed by a healthcare professional.

GNH India supplies Ivermectine Pierre Fabre as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pierre Fabre Medicament

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Indications & Clinical Uses

  • Ivermectin acts on a broad spectrum of parasitic organisms, interrupting their neuromuscular function.
  • Onchocerciasis: eliminates microfilariae to prevent skin and eye disease.
  • Strongyloidiasis: eradicates intestinal larvae to resolve chronic infection.
  • Scabies: kills Sarcoptes mites, relieving itching and skin lesions.
  • Lymphatic filariasis: reduces adult worm burden to control disease transmission.
  • Other helminth infections: treats various nematode infestations as indicated.

How It Works

  • Ivermectin binds selectively to glutamate‑gated chloride channels found in invertebrate nerve and muscle cells. This binding increases the permeability of the cell membrane to chloride ions, causing hyperpolarization, paralysis and ultimately death of the parasite, while having minimal affinity for mammalian receptors.

Side Effects

Ivermectin is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Mild itching or rash at the site of infection.
  • Nausea or abdominal discomfort.
  • Diarrhea.
  • Dizziness or headache.
  • Transient fever.

Serious or Rare Side Effects

  • Severe skin reactions such as Stevens‑Johnson syndrome.
  • Neurological signs including seizures or altered consciousness.
  • Hepatotoxicity with elevated liver enzymes.
  • Visual disturbances.
  • Severe hypotension.

Precautions & Warnings

  • Before initiating therapy, consider the following precautions.
  • Pregnancy: Use only if the potential benefit outweighs the risk, as safety data are limited.
  • Breastfeeding: Caution advised; consult a healthcare professional.
  • Co‑administration with other antiparasitics: Monitor for additive toxicity.
  • Renal or hepatic impairment: Dose adjustment may be required under medical supervision.
  • Drug interactions: Review concomitant medications for potential interactions.
  • Store at ambient temperature: Keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Ivermectin may interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampicin) that may reduce efficacy.
  • Concomitant use with other neurotoxic agents increasing risk of CNS effects.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: may enhance anticoagulant effect.
  • P‑glycoprotein inhibitors: could increase ivermectin plasma levels.
  • Other antiparasitic agents: assess cumulative toxicity.

Frequently Asked Questions

Ivermectine Pierre Fabre contains ivermectin, which is indicated for the treatment of onchocerciasis, strongyloidiasis, scabies, lymphatic filariasis and other helminth infections. It works by targeting the parasites responsible for these diseases, helping to eliminate the infection under medical supervision.

Ivermectin binds to glutamate‑gated chloride channels in the nervous system of parasites. This increases chloride ion flow, causing hyperpolarization of nerve or muscle cells, leading to paralysis and death of the parasite while sparing human cells.

The dosage of Ivermectine Pierre Fabre is determined by the prescribing clinician based on the specific infection, patient weight, age and local treatment guidelines. Only a qualified healthcare professional should set the appropriate dose.

Safety data for ivermectin in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ivermectin offers a broad spectrum of activity against many nematodes and ectoparasites, often with a single dose regimen. Compared with alternatives such as albendazole or praziquantel, ivermectin may have a different safety profile and is preferred for certain infections like onchocerciasis and scabies.

Store Ivermectine Pierre Fabre at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Ivermectine Pierre Fabre is administered orally, usually as a tablet taken with water. The exact administration instructions, including whether to take it with food, are provided by the prescribing clinician.

Serious adverse reactions, though rare, can include severe skin reactions such as Stevens‑Johnson syndrome, neurological events like seizures or altered consciousness, and significant liver enzyme elevations. Patients should seek immediate medical attention if any of these symptoms develop.

Individuals with known hypersensitivity to ivermectin or any component of the formulation should avoid the product. Additionally, patients with certain neurological disorders or those taking contraindicated medications should not use it without medical advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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