Product image of Ivermectine Xiromed (Ivermectin) supplied by GNH India

Ivermectine Xiromed

Active Ingredient:
Ivermectin
Origin:
EU

Ivermectine Xiromed (Ivermectin)

Ivermectin, the active ingredient in Ivermectine Xiromed, is an anthelmintic presented as an oral formulation for oral use. It treats a range of parasitic infections including onchocerciasis, strongyloidiasis, scabies, lymphatic filariasis and other helminth infections.

GNH India supplies Ivermectine Xiromed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Medical Valley Invest Ab

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Indications & Clinical Uses

Ivermectin is an anthelmintic that targets a variety of parasitic infections.

  • Onchocerciasis: reduces microfilariae load and prevents disease progression.
  • Strongyloidiasis: eliminates intestinal larvae and prevents dissemination.
  • Scabies: eradicates Sarcoptes scabiei mites, relieving skin infestation.
  • Lymphatic filariasis: clears filarial worms, reducing morbidity.
  • Other helminth infections: treats various nematode infections, improving patient outcomes.

How It Works

  • Ivermectin binds selectively to glutamate‑gated chloride channels in the nerve and muscle cells of invertebrates. This binding increases chloride ion influx, causing hyperpolarization of the cell membrane, leading to paralysis and eventual death of the parasite without affecting mammalian cells.

Side Effects

Ivermectin may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea
  • Diarrhea
  • Dizziness
  • Itching

Serious or Rare Side Effects

  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Neurological effects including seizures
  • Hepatotoxicity
  • Anaphylaxis

Precautions & Warnings

Before prescribing Ivermectine Xiromed, clinicians should consider several safety measures.

  • Assess for known hypersensitivity: avoid in patients with documented ivermectin allergy.
  • Monitor liver function: use caution in patients with hepatic impairment.
  • Review concomitant CNS‑active drugs: potential for enhanced neurotoxicity.
  • Use with caution in patients with compromised blood‑brain barrier.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ivermectin can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampicin) may reduce ivermectin exposure.
  • P‑glycoprotein inhibitors (e.g., verapamil) may increase ivermectin levels.
  • Concurrent use with other neurotoxic antiparasitics may heighten neurotoxicity.

Moderate Interactions (Monitor Closely)

  • Macrolide antibiotics (e.g., erythromycin) may modestly raise ivermectin concentrations.
  • Warfarin may have enhanced anticoagulant effect; monitor INR closely.

Frequently Asked Questions

Ivermectine Xiromed contains ivermectin, an antiparasitic medication used to treat onchocerciasis (river blindness), strongyloidiasis, scabies, lymphatic filariasis and a variety of other helminth infections. It is prescribed by qualified healthcare professionals based on the specific parasitic disease diagnosed.

Ivermectin works by binding to glutamate‑gated chloride channels in the nerve and muscle cells of invertebrate parasites. This binding increases chloride ion influx, leading to hyperpolarization, paralysis, and ultimately death of the parasite, while having minimal effect on human cells.

The dosage of Ivermectine Xiromed is determined by the prescribing clinician based on the patient’s age, weight, the specific infection being treated, and regional treatment guidelines. Patients should follow the exact dosing instructions provided by their healthcare provider.

The safety of ivermectin during pregnancy and lactation has not been definitively established. It is classified as pregnancy category unknown, and clinicians usually weigh potential benefits against risks before prescribing to pregnant or nursing women.

To order Ivermectine Xiromed, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ivermectin belongs to the macrocyclic lactone class and offers a broad spectrum of activity against many nematodes and ectoparasites. Compared with older agents such as albendazole or praziquantel, ivermectin often requires fewer doses and has a well‑characterized safety profile, though choice of therapy depends on the specific parasite and regional resistance patterns.

Ivermectine Xiromed should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Ivermectine Xiromed is administered orally, typically as a tablet or liquid formulation. The exact method of intake—such as with or without food—should follow the prescribing clinician’s instructions to ensure optimal absorption and efficacy.

Serious adverse events, although rare, can include severe skin reactions like Stevens‑Johnson syndrome, neurological complications such as seizures, hepatotoxicity, and anaphylactic reactions. Patients should seek immediate medical attention if they experience any signs of these severe reactions.

Ivermectine Xiromed should be avoided in individuals with a known hypersensitivity to ivermectin or any component of the formulation. Caution is also advised for patients with severe hepatic impairment, compromised blood‑brain barrier, or those taking medications that strongly interact with ivermectin.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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