Product image of Ivohart (Ivabradine Hydrochloride) supplied by GNH India

Ivohart

Active Ingredient:
Ivabradine Hydrochloride
Origin:
EU

Ivohart (Ivabradine Hydrochloride)

Ivabradine Hydrochloride, the active ingredient in Ivohart, is an If channel inhibitor presented as a tablet for oral use. It treats chronic stable angina and heart failure with reduced ejection fraction in adults.

GNH India supplies Ivohart as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch Health Ireland Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Ivohart acts on the cardiac If current to manage ischemic heart conditions and heart failure.
  • Chronic stable angina: reduces the frequency of angina attacks and improves exercise tolerance.
  • Heart failure with reduced ejection fraction: lowers heart rate, improves symptoms and may reduce hospitalizations.
  • Ischemic heart disease: helps control heart rate without compromising contractility.

How It Works

  • Ivabradine selectively inhibits the funny (If) current in the sinoatrial node, which slows spontaneous depolarization. This results in a reduction of resting heart rate while preserving myocardial contractility and blood pressure, thereby decreasing myocardial oxygen demand in patients with angina or heart failure.

Side Effects

Adverse reactions may occur with ivabradine therapy.

Common Side Effects

  • Visual disturbances (phosphenes)
  • Bradycardia
  • Headache
  • Dizziness
  • Fatigue
  • Blurred vision

Serious or Rare Side Effects

  • Symptomatic bradycardia requiring medical intervention
  • Atrial fibrillation or other arrhythmias
  • Severe hypotension
  • Myocardial infarction
  • Heart block
  • Persistent visual impairment

Precautions & Warnings

  • Use ivabradine with caution in specific clinical situations.
  • Cardiac monitoring: patients with baseline heart rate below 60 bpm should be observed.
  • Concomitant bradycardic agents: avoid excessive heart‑rate reduction when combined with beta‑blockers or digoxin.
  • Severe hepatic impairment: dose adjustment may be required.
  • Pregnancy and lactation: contraindicated unless benefits outweigh risks.
  • Drug interactions: review concomitant CYP3A4 inhibitors before prescribing.
  • Store at ambient temperature: keep in the original pack, protect from moisture and light.

Avoid Interactions

Ivabradine may interact with several medicines that affect heart rate or metabolism.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may increase ivabradine plasma levels.
  • Concomitant bradycardic agents (e.g., beta‑blockers, digoxin): risk of excessive bradycardia.
  • Other If channel inhibitors: additive heart‑rate lowering effect.

Moderate Interactions (Monitor Closely)

  • Moderate CYP3A4 inhibitors (e.g., erythromycin): may require dose adjustment.
  • Antihypertensives: potential enhanced blood‑pressure reduction.
  • QT‑prolonging drugs: monitor ECG for arrhythmia risk.

Frequently Asked Questions

Ivohart (ivabradine hydrochloride) is prescribed for chronic stable angina and for heart failure with reduced ejection fraction, helping to lower heart rate and improve symptoms in these cardiovascular conditions.

Ivabradine selectively blocks the funny (If) current in the sinoatrial node, slowing the pacemaker activity of the heart. This reduces resting heart rate without affecting the strength of cardiac contraction, decreasing myocardial oxygen demand.

The dosage of Ivohart is determined by the prescribing physician based on the patient’s clinical condition, heart‑rate response, and tolerance. Dosage adjustments are made according to individual therapeutic needs.

Ivabradine is generally contraindicated in pregnancy and lactation unless the potential benefit justifies the risk. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To order Ivohart, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike beta‑blockers or calcium‑channel blockers, ivabradine lowers heart rate by targeting the If current without reducing myocardial contractility or blood pressure, making it a useful adjunct when additional heart‑rate control is needed.

Ivohart tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the container tightly closed and out of reach of children.

Ivohart is taken orally, usually with a glass of water. The tablet should be swallowed whole and not split, crushed, or chewed unless otherwise instructed by a healthcare professional.

Serious risks include symptomatic bradycardia, atrial fibrillation, severe hypotension, heart block, and rare visual disturbances. Patients should be monitored for these events, especially when combined with other heart‑rate‑lowering agents.

Ivohart should be avoided in patients with a resting heart rate below 60 bpm, severe hepatic impairment, acute decompensated heart failure, sick sinus syndrome, or those taking strong CYP3A4 inhibitors without appropriate dose adjustment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Ivabradine Hydrochloride

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT