Product image of Izba (Travoprost) supplied by GNH India

Izba

Active Ingredient:
Travoprost
Origin:
EU

Izba (Travoprost)

Travoprost, the active ingredient in Izba, is a prostaglandin analog formulated as an ophthalmic solution for ocular administration. It is indicated for the reduction of elevated intraocular pressure in adults diagnosed with primary open-angle glaucoma or ocular hypertension, helping to preserve visual function.

GNH India supplies Izba as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide under strict quality standards. The product complies with European Union marketing authorisation requirements and is distributed under controlled conditions to ensure integrity throughout the supply chain.

Manufacturer / TM Owner

Novartis Europharm Limited

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Indications & Clinical Uses

  • Travoprost is a prostaglandin analog used to manage ocular hypertension and glaucoma by enhancing aqueous humor outflow.
  • Primary open-angle glaucoma: reduces intraocular pressure to slow disease progression.
  • Ocular hypertension: lowers elevated eye pressure to prevent conversion to glaucoma.
  • Secondary open-angle glaucoma: assists in lowering pressure when caused by other ocular conditions.

How It Works

  • Travoprost acts as a selective prostaglandin F (FP) receptor agonist in the ciliary body. Activation of FP receptors increases uveoscleral outflow of aqueous humor, thereby facilitating drainage of fluid from the eye and resulting in a sustained reduction of intraocular pressure.

Side Effects

Common Side Effects

  • Eye redness: transient hyperemia of the conjunctiva.
  • Eyelash changes: increased length or thickness of lashes.
  • Eye irritation: burning or stinging sensation after instillation.
  • Darkening of iris: gradual increase in brown pigmentation.

Serious or Rare Side Effects

  • Macular edema: swelling of the central retina that may affect vision.
  • Anterior uveitis: inflammation of the front structures of the eye.
  • Severe allergic reaction: swelling, itching, or rash around the eye.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Monitor intraocular pressure: measure regularly after starting treatment.
  • Assess for ocular infections: avoid use if an active eye infection is present.
  • Avoid contact lens wear: discontinue lenses before and after instillation.
  • Use with caution in patients with cystoid macular edema.
  • Pregnancy and lactation: safety not established; weigh potential risks and benefits.
  • Store at room temperature: keep the bottle in its original packaging, protect from light and moisture.

Avoid Interactions

Travoprost may interact with other ocular or systemic agents. Review the following interactions:

Major Interactions (Avoid)

  • Non‑steroidal anti‑inflammatory eye drops: may reduce Travoprost efficacy.
  • Systemic carbonic anhydrase inhibitors: additive intraocular pressure‑lowering effect, requiring pressure monitoring.
  • Beta‑blocker eye drops: combined use can cause excessive pressure reduction.

Moderate Interactions (Monitor Closely)

  • Other prostaglandin analogs: avoid simultaneous use due to overlapping mechanisms.
  • Topical corticosteroids: may diminish the intraocular pressure‑lowering effect of Travoprost.

Frequently Asked Questions

Izba contains travoprost, a prostaglandin analog indicated for the treatment of primary open-angle glaucoma and ocular hypertension. By lowering intraocular pressure, it helps to prevent optic nerve damage and preserve visual function in patients with these conditions.

Travoprost binds to prostaglandin F (FP) receptors in the eye’s ciliary body. This activation enhances uveoscleral outflow of aqueous humor, increasing drainage from the anterior chamber and resulting in a sustained reduction of intraocular pressure.

The dosing regimen for Izba is determined by the prescribing clinician. Typically, one drop is instilled into the affected eye(s) once daily, but the exact dose and timing should follow the prescriber’s instructions.

Safety data for travoprost in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by the treating physician.

To request Izba, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Izba (travoprost) belongs to the prostaglandin analog class, which generally offers once‑daily dosing and strong intraocular pressure reduction. Compared with beta‑blocker drops, prostaglandin analogs tend to have a more favorable dosing schedule and comparable efficacy, though individual response may vary.

Store Izba eye‑drop bottles at room temperature, away from direct sunlight and moisture. Keep the container tightly closed when not in use and retain it in the original packaging to protect the solution from contamination.

Tilt the head back slightly, pull down the lower eyelid to create a small pocket, and instill one drop of Izba into the conjunctival sac. Close the eye gently for a few seconds, avoid touching the tip of the bottle to the eye or any surface, and wash hands afterward.

Serious but rare adverse events include macular edema, anterior uveitis, and severe allergic reactions such as swelling or rash around the eye. Patients should seek immediate medical attention if they experience sudden vision changes, eye pain, or signs of an allergic response.

Izba should not be used by individuals with known hypersensitivity to travoprost or any component of the formulation, and it is contraindicated in eyes with active intraocular infection or inflammation. Caution is also advised for patients with a history of cystoid macular edema.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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