Product image of Izifet (Levothyroxine Sodium) supplied by GNH India

Izifet

Active Ingredient:
Levothyroxine Sodium
Origin:
EU

Izifet (Levothyroxine Sodium)

Levothyroxine Sodium, the active ingredient in Izifet, is a thyroid hormone presented as an oral tablet for systemic use. It replaces deficient endogenous thyroid hormone and is used to treat hypothyroidism, thyroid hormone replacement therapy, and goiter in adults and children.

GNH India supplies Izifet as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and procurement teams worldwide, ensuring quality and regulatory compliance across markets. Our distribution network adheres to stringent quality standards and supports timely delivery to healthcare providers.

Manufacturer / TM Owner

Nassington Ltd

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Levothyroxine Sodium is used to restore normal thyroid hormone levels in conditions affecting the thyroid gland.

  • Hypothyroidism: restores deficient thyroid hormone, normalizing metabolism and alleviating symptoms such as fatigue and weight gain.
  • Thyroid hormone replacement therapy after thyroidectomy or radioactive iodine: provides the necessary hormone to maintain metabolic homeostasis.
  • Goiter associated with thyroid hormone deficiency: reduces gland enlargement by correcting hormonal imbalance.

How It Works

  • Levothyroxine Sodium is a synthetic form of thyroxine (T4) that is absorbed from the gastrointestinal tract and circulates bound to plasma proteins. Within target cells, deiodinase enzymes convert it to the active triiodothyronine (T3). The resulting hormone binds nuclear thyroid hormone receptors, modulating gene transcription that regulates basal metabolic rate, protein synthesis, and growth.

Side Effects

Levothyroxine Sodium may cause a range of adverse reactions, which are grouped by frequency and severity.

Common Side Effects

  • Headache
  • Insomnia
  • Palpitations
  • Weight loss
  • Heat intolerance
  • Tremor

Serious or Rare Side Effects

  • Allergic reaction (rash, angioedema)
  • Chest pain or arrhythmia
  • Severe hyperthyroidism symptoms
  • Bone loss (osteoporosis) with long‑term overtreatment

Precautions & Warnings

When prescribing Levothyroxine Sodium, clinicians should consider several safety measures.

  • Monitor thyroid function tests regularly: adjust dose based on TSH and free T4 levels.
  • Initiate therapy with low dose in elderly patients: reduce risk of cardiac stress.
  • Avoid use in untreated adrenal insufficiency: may precipitate adrenal crisis.
  • Caution during pregnancy and breastfeeding: weigh benefits against potential fetal thyroid effects.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Levothyroxine Sodium can interact with various medicines that affect its absorption or metabolism.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: decrease levothyroxine absorption.
  • Calcium supplements or calcium carbonate: bind levothyroxine and reduce bioavailability.
  • Iron salts (ferrous sulfate): impair absorption when taken concurrently.
  • Cholesterol‑lowering resins (e.g., cholestyramine): sequester levothyroxine.
  • Amiodarone: alters thyroid hormone metabolism and may require dose adjustment.

Moderate Interactions (Monitor Closely)

  • Warfarin: levothyroxine may enhance anticoagulant effect, monitor INR.
  • Corticosteroids: may increase levothyroxine clearance, watch thyroid levels.
  • Estrogen therapy (including oral contraceptives): may raise levothyroxine requirement.

Frequently Asked Questions

Izifet contains Levothyroxine Sodium, which is prescribed to replace deficient thyroid hormone in patients with hypothyroidism, to provide hormone after thyroidectomy or radioactive iodine treatment, and to treat goiter caused by hormonal imbalance.

Levothyroxine Sodium is a synthetic form of the natural hormone T4. After oral absorption it is converted to the active hormone T3 inside cells, where it binds nuclear thyroid receptors and regulates gene expression that controls metabolism, growth and development.

The appropriate dose of Izifet is individualized by the prescribing clinician based on the patient’s age, weight, severity of thyroid deficiency, and periodic laboratory measurements of TSH and free T4. No fixed regimen is provided here.

Levothyroxine Sodium is classified as a pregnancy category that requires careful risk‑benefit assessment. It is often continued in pregnancy to maintain maternal euthyroidism, which is important for fetal development. Breastfeeding mothers should discuss continuation with their healthcare provider.

To request Izifet, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Izifet delivers the same active ingredient, Levothyroxine Sodium, as other branded or generic levothyroxine products. Differences may lie in manufacturing standards, excipients, and regulatory approvals. Clinical efficacy and safety are comparable when bioequivalence is demonstrated.

Store Izifet at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture, heat and direct light. Do not store in the bathroom or near a kitchen sink.

Izifet is taken orally, usually on an empty stomach, at least 30 minutes before breakfast. The tablet should be swallowed whole with a full glass of water. Patients should follow the dosing schedule prescribed by their healthcare professional.

Serious adverse events include signs of overt hyperthyroidism such as chest pain, arrhythmia, severe tremor, or unexplained weight loss, as well as allergic reactions like rash or swelling. Any of these symptoms require immediate medical evaluation.

Izifet should be avoided in individuals with untreated adrenal insufficiency, acute myocardial infarction, or known hypersensitivity to levothyroxine or any tablet excipients. Patients with these conditions should discuss alternative therapies with their physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Levothyroxine Sodium

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT