Product image of Izinova (Magnesium Sulfate Heptahydrate, Sodium Sulfate Anhydrous, Potassium Sulphate) supplied by GNH India

Izinova

Active Ingredient:
Magnesium Sulfate Heptahydrate, Sodium Sulfate Anhydrous, Potassium Sulphate
Origin:
EU

Izinova (Magnesium Sulfate Heptahydrate, Sodium Sulfate Anhydrous, Potassium Sulphate)

Magnesium sulfate, sodium sulfate and potassium sulfate, the active ingredients in Izinova, are a mineral salt combination presented as an oral formulation for oral use. It provides electrolyte supplementation and a mild laxative effect in adults.
GNH India supplies Izinova as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mayoly Pharma France

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Indications & Clinical Uses

Izinova, a combination of mineral salts, is used to address electrolyte balance and bowel function.

  • Constipation: provides osmotic laxative action to facilitate bowel movements.
  • Hypomagnesemia: supplies magnesium to help correct deficiency.
  • Electrolyte imbalance: delivers sodium and potassium to assist restoration of normal electrolyte levels.

How It Works

  • The magnesium and sodium sulfates act as osmotic agents that retain water within the intestinal lumen, increasing stool volume and promoting peristalsis. Potassium sulfate contributes potassium ions, helping to replenish extracellular potassium and supporting overall electrolyte homeostasis while the combined salts modestly stimulate bowel motility.

Side Effects

Izinova may cause a range of adverse reactions, most of which are mild and related to its osmotic activity.

Common Side Effects

  • Abdominal cramping
  • Diarrhea
  • Nausea
  • Flatulence
  • Mild electrolyte disturbances (e.g., transient low sodium)

Serious or Rare Side Effects

  • Severe dehydration
  • Hypermagnesemia
  • Hyperkalemia
  • Significant electrolyte imbalance
  • Allergic reaction or anaphylaxis
  • Acute renal impairment in susceptible individuals

Precautions & Warnings

Before using Izinova, consider the following safety measures.

  • Assess renal function: impaired clearance may increase risk of electrolyte accumulation.
  • Monitor serum electrolytes: especially magnesium, potassium and sodium levels during therapy.
  • Use with caution in heart‑failure patients: fluid shifts may affect cardiac status.
  • Avoid in complete bowel obstruction: risk of perforation or worsening obstruction.
  • Pregnancy: consult a healthcare provider before use.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Izinova can interact with other medicines that affect electrolyte balance or gastrointestinal motility.

Major Interactions (Avoid)

  • Potassium‑sparing diuretics: may cause dangerous hyperkalemia.
  • Calcium channel blockers: enhanced magnesium effects can lead to hypotension.
  • Other osmotic laxatives: risk of severe electrolyte loss.

Moderate Interactions (Monitor Closely)

  • Digoxin: altered potassium levels may affect drug activity.
  • ACE inhibitors: monitor potassium to avoid excess.
  • Antacids containing magnesium or aluminum: may affect absorption of the salts.

Frequently Asked Questions

Izinova is an oral formulation that combines magnesium sulfate, sodium sulfate and potassium sulfate. It is used to help restore electrolyte balance and to provide a mild osmotic laxative effect for the relief of occasional constipation in adults.

The sulfates act as osmotic agents that draw water into the intestinal lumen, increasing stool bulk and promoting peristalsis. At the same time, the salts supply magnesium, sodium and potassium ions, supporting normal electrolyte concentrations in the body.

The appropriate dose of Izinova is determined by the prescribing healthcare professional based on the individual’s clinical condition, age, renal function and electrolyte status. Patients should follow the specific instructions provided by their prescriber.

Safety of Izinova in pregnancy or while breastfeeding has not been fully established. Women who are pregnant, planning to become pregnant, or nursing should discuss potential risks and benefits with their healthcare provider before using the product.

To order Izinova, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Izinova differs from many single‑ingredient laxatives by providing a combination of magnesium, sodium and potassium salts, which not only act as an osmotic laxative but also help replenish key electrolytes. This dual function can be advantageous for patients who need both bowel regulation and electrolyte support.

Izinova should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight and excessive heat to maintain its stability and effectiveness.

Izinova is taken orally, usually with a full glass of water. The exact administration schedule, including timing relative to meals, should follow the prescribing clinician’s directions.

Serious risks include severe dehydration, hypermagnesemia, hyperkalemia and significant electrolyte imbalance, especially in patients with renal impairment or those taking interacting medications. Prompt medical attention is required if symptoms such as muscle weakness, irregular heartbeat or extreme thirst develop.

Izinova should be avoided in individuals with severe renal failure, complete bowel obstruction, known hypersensitivity to any of its components, or in patients taking medications that could cause dangerous electrolyte disturbances without close monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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